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Concentration QT Interval Modeling of Intranasally Administered Zavegepant in Healthy Subjects

Author:Bertz, Richard   Stringfellow, Joseph   Bhardwaj, Rajinder   Donohue, Mary   Madonia, Jennifer   Anderson, Matt   Morris, Beth   Coric, Vladimir   Croop, Robert   

Session Name:P9: Headache: The Gepant Pipeline  

Topic:Headache  

Program Number:P9.004  

Author Institution:Biohaven Pharmaceuticals, New Haven, CT  Navitas Data Sciences, Pottstown, PA  Certara USA, Princeton, NJ  

Effects of Zavegepant and Concomitant Sumatriptan on Blood Pressure and Pharmacokinetics in Healthy Adult Participants

Author:Bertz, Richard   Bhardwaj, Rajinder   Donohue, Mary   Madonia, Jennifer   Stringfellow, Joseph   Anderson, Matt   Morris, Beth   Coric, Vladimir   Croop, Robert   

Session Name:P9: Headache: The Gepant Pipeline  

Topic:Headache  

Program Number:P9.005  

Author Institution:Biohaven Pharmaceuticals, New Haven, CT  Certara USA, Princeton, NJ  Navitas Data Sciences, Pottstown, PA  

Pharmacokinetics, Disposition, and Biotransformation of 5 mg [14C]-Zavegepant in Healthy Male Subjects After a Single Intravenous Infusion Dose

Author:Bhardwaj, Rajinder   Donohue, Mary   Stringfellow, Joseph   Madonia, Jennifer   Anderson, Matt   Morris, Beth   Coric, Vladimir   Croop, Robert   Bertz, Richard   

Session Name:P9: Headache: The Gepant Pipeline  

Topic:Headache  

Program Number:P9.008  

Author Institution:Certara USA, Princeton, NJ  Biohaven Pharmaceuticals, New Haven, CT  Navitas Data Sciences, Pottstown, PA  

Effects of the Strong CYP3A4 and P-glycoprotein Inhibitor Itraconazole on the Pharmacokinetics of Oral and Intranasal Zavegepant

Author:Bhardwaj, Rajinder   Malatesta, Jo Ann   Stringfellow, Joseph   Madonia, Jennifer   Anderson, Matt   Morris, Beth   Coric, Vladimir   Croop, Robert   Bertz, Richard   

Session Name:P9: Headache: The Gepant Pipeline  

Topic:Headache  

Program Number:P9.011  

Author Institution:Certara USA, Princeton, NJ  Navitas Data Sciences, Pottstown, PA  Biohaven Pharmaceuticals, New Haven, CT