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The Integrated Stress Response Is Modulated by eIF2B Agonist DNL343: Results From Phase 1 Healthy Subject and Phase 1b ALS Patient Studies.

Author:Sun, Linus   Tsai, Richard   Yulyaningsih, Ernie   Fanok, Melania   Vissers, Maurits   Heuberger, Jules   Flores, Brittany   Huang, Fen   Kane, Lesley   Cohen, Isaac   Dhuria, Shyeilla   Fang, Meng   Estrada, Anthony   Osipov, Maksim   Willman-Yoswa, Brent   Maciuca, Romeo   Dobbins, Sarah   Chau, Ronnie   Earr, Timothy   Nguyen, Hoang   Lopez, Isabel   Scearce-Levie, Kimberly   Bunte, Tommy   Van den Berg, Leonard   Ho, Carole   Groeneveld, Geert-Jan   Troyer, Matthew   

Session Name:P8: Neuromuscular Disease: Amyotrophic Lateral Sclerosis 1  

Topic:Neuromuscular and Clinical Neurophysiology (EMG)  

Program Number:P8.010  

Author Institution:Denali Therapeutics, South San Francisco, CA  Denali Therapeutics, San Francisco, CA  Centre for Human Drug Research/Leiden University Medical Center, Leiden, Netherlands  Denali Therapeutics, South Sa, CA  Denali Therapeutics, South San Francisco, NY  University Medical Centre Utrecht, Utrecht, Netherlands