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PRAX-562 is a Well-Tolerated, Novel Persistent Sodium Channel Blocker with Broad Anticonvulsant Activity in Multiple DEE Mouse Models

Author:Anderson, Lyndsey   Jancovski, Nikola   Eckert, William   Baker, Erin   Wagley, Pravin   Maljevic, Snezana   Reid, Christopher   Patel, Manoj   Kearney, Jennifer   Kahlig, Kristopher   Petrou, Steven   

Session Name:S34: Child Neurology and Developmental Neurology 2  

Topic:Child Neurology and Developmental Neurology  

Program Number:S34.007  

Author Institution:Praxis Precision Medicines, Boston, MA  Florey Institute of Neuroscience and Mental Health, Parkville, Australia  Northwestern University Feinberg School of Medicine, Chicago, IL  University of Virginia Health System, Charlottesville, VA  

PRAX-628 is a Novel, Well-Tolerated, Activity Dependent Sodium Channel Blocker with Potent Anticonvulsant Activity

Author:Eckert, William   Kahlig, Kristopher   Anderson, Lyndsey   Petrou, Steven   

Session Name:P4: Child Neurology and Developmental Neurology: Seizures 2  

Topic:Child Neurology and Developmental Neurology  

Program Number:P4.012  

Author Institution:Praxis Precision Medicines, Boston, MA  

Treatment Outcomes for Patients With Amyotrophic Lateral Sclerosis Receiving Intravenous Edaravone From a Home and Alternative-Site Infusion Provider

Author:Da Silva, Polina   Ciepielewska, Malgorzata   Do, Quan   Anderson, Marlena   Martin, Karen   Ortlip, Kayla Janovsky   

Session Name:P6: General Neurology: New Treatments  

Topic:General Neurology  

Program Number:P6.005  

Author Institution:Mitsubishi Tanabe Pharma America, Inc., Jersey City, NJ  Amerita, Greenwood Village, CO  

Concentration QT Interval Modeling of Intranasally Administered Zavegepant in Healthy Subjects

Author:Bertz, Richard   Stringfellow, Joseph   Bhardwaj, Rajinder   Donohue, Mary   Madonia, Jennifer   Anderson, Matt   Morris, Beth   Coric, Vladimir   Croop, Robert   

Session Name:P9: Headache: The Gepant Pipeline  

Topic:Headache  

Program Number:P9.004  

Author Institution:Biohaven Pharmaceuticals, New Haven, CT  Navitas Data Sciences, Pottstown, PA  Certara USA, Princeton, NJ  

Effects of Zavegepant and Concomitant Sumatriptan on Blood Pressure and Pharmacokinetics in Healthy Adult Participants

Author:Bertz, Richard   Bhardwaj, Rajinder   Donohue, Mary   Madonia, Jennifer   Stringfellow, Joseph   Anderson, Matt   Morris, Beth   Coric, Vladimir   Croop, Robert   

Session Name:P9: Headache: The Gepant Pipeline  

Topic:Headache  

Program Number:P9.005  

Author Institution:Biohaven Pharmaceuticals, New Haven, CT  Certara USA, Princeton, NJ  Navitas Data Sciences, Pottstown, PA