Fenfluramine Treatment Is Associated With Improvement in Everyday Executive Function in Adults With Lennox-Gastaut Syndrome: Post-Hoc Analysis of Dose Effects From a Phase 3 Trial Rationale

Author:Bishop, Kim   Isquith, Peter   Knupp, Kelly   Sullivan, Joseph   Nabbout, Rima   Gil-Nagel, Antonio   Scheffer, Ingrid   Auvin, Stéphane   Cross, J Helen   Guerrini, Renzo   Roth, Robert   Gioia, Gerard   Lothe, Amélie   Polega, Shikha   

Session Name:P11: Epilepsy/Clinical Neurophysiology (EEG): ASMs Clinical Trial 1  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P11.001  

Author Institution:Global Pharma Consultancy, LLC, Muncy, PA  Global Pharma Consultancy, LLC  Boston Children’s Hospital, Harvard Medical School, Boston, MA  Children's Hospital Colorado, Aurora, CO  University of California San Francisco, Benioff Children’s Hospital, San Francisco, CA  Reference Centre for Rare Epilepsies, Hôpital Universitaire Necker-Enfants Malades, APHP, Member of EPICARE, Institut Imagine, Université Paris Cité, Paris, France  Hospital Ruber Internacional, Madrid, Spain  University of Melbourne, Austin Hospital and Royal Children’s Hospital, Florey Institute and Murdoch Children’s Research Institute, Heidelberg, Australia  Robert Debré University Hospital, APHP, Université de Paris, Institut Universitaire de France (IUF), Paris, France  UCL NIHR BRC Great Ormond Street Institute of Child Health, London, United Kingdom  Anna Meyer Children's Hospital, University of Florence, Milan, Italy  Dartmouth-Hitchcock Medical Center, Lebanon, NH  Children’s National Health System, Rockville, MD  Zogenix International (now a part of UCB), Maidenhead, United Kingdom  Zogenix, Inc. (now a part of UCB), Emeryville, CA  

Efficacy of Soticlestat Treatment by Seizure Type in Patients with Dravet Syndrome or Lennox–Gastaut Syndrome in a Phase 2, Randomized, Placebo-controlled Study (ELEKTRA)

12-Month Effectiveness and Tolerability of Brivaracetam in the Real-World: The International EXPERIENCE Pooled Analysis

Author:Villanueva, Vicente   D'Souza, Wendyl   Faught, Edward   Klein, Pavel   Reuber, Markus   Rosenow, Felix   Salas-Puig, Javier   Soto Insuga, Victor   Strzelczyk, Adam   Szaflarski, Jerzy P.   Besson, Herve   Daniels, Tony   Floricel, Florin   Laloyaux, Cedric   Sendersky, Veronica   Zhou, Sophia   Steinhoff, Bernhard J.   

Session Name:P11: Epilepsy/Clinical Neurophysiology (EEG): ASMs Clinical Trial 1  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P11.003  

Author Institution:Hospital Universitario y Politécnico La Fe, Valencia, Spain, Valencia, Spain  Department of Medicine, St Vincent’s Hospital Melbourne, The University of Melbourne, Melbourne, Australia, Melbourne, Australia  Emory Epilepsy Center, Atlanta, GA, USA, Atlanta, GA  Mid-Atlantic Epilepsy and Sleep Center, Bethesda, MD, USA, Bethesda, MD  The University of Sheffield, Sheffield, UK, Sheffield, United Kingdom  Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Frankfurt, Germany, Frankfurt am Main, Germany  Universitari Vall d’Hebron, Barcelona, Spain, Barcelona, Spain  Pediatric Neurology, Hospital Universitario Infantil Niño Jesús, Madrid, Spain, Madrid, Spain  Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Frankfurt, Germany, Frankfurt, Germany  UAB Epilepsy Center, Birmingham, AL, USA, Birmingham, AL  UCB Pharma, Breda, Netherlands, Breda, Netherlands  UCB Pharma, Morrisville, NC, USA, Morrisville, NC  UCB Pharma, Monheim am Rhein, Germany, Monheim Am Rhein, Germany  UCB Pharma, Brussels, Belgium, Brussels, Belgium  Kork Epilepsy Center, Kehl-Kork and Medical Faculty, University of Freiburg, Freiburg, Germany, Kork, Germany  

Early and Sustained Treatment Effect of Adjunctive Perampanel in Patients with Seizures Associated with Lennox-Gastaut Syndrome (LGS): A Post Hoc Analysis