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Interferome perturbation of human brain organoids induces progenitor and neuronal dysfunction seen in multiple sclerosis and autism

Author:Hollingsworth, Ethan   Julian, Dominic   Watanabe, Fumihiro   Reutershan, Trevor   Julian, Katie   Martorell Serra, Ivette   Lizarraga, Sofia   Hester, Mark   Imitola, Jaime   

Session Name:P2: MS Immunology and Basic Science  

Topic:MS and Inflammatory Disease  

Program Number:P2.015  

Author Institution:University of California Irvine, Irvine, CA  Univ of Arizona School of Medicine, Phoenix, AZ  UCONN Health, West Hartford, CT  Penn State Univ School of Medicine, Hershey, PA  Thomas Jefferson, Philadelphia, PA  Univ of South Carolina, Columbia, SC  Nationwide Children's Hospital, Columbus, OH  UConn Health MS center , Farmington, CT  

Modeling of Aryl Hydrocarbon Receptor Pathway Intrinsic Immunometabolic Role using Glioblastoma Stem Cells and Patient-Derived Organoids

Author:Watanabe, Fumihiro   Hollingsworth, Ethan   Bartley, Jenna   Schiapparelli, Paula   Quiñones-Hinojosa, Alfredo   Imitola, Jaime   

Session Name:P11: Neuro-oncology: Genetics and Biology of Brain Tumors  

Topic:Neuro-oncology  

Program Number:P11.004  

Author Institution:UCONN Health, West Hartford, CT  University of California Irvine, Irvine, CA  UConn Health, Farmington, CT  Mayo Clinic, Jacksonville, FL  UConn Health MS center , Farmington, CT