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              Immunological Signatures Associated With Ocrelizumab Treatment in Early RRMS: 12-Month Interim Analysis From the Ocrelizumab Phase IIIb (ENSEMBLE; NCT03085810) Immunological Substudy

              Author:Wirth, Timo   Schulte-Mecklenbeck, Andreas   Steinberg, Olgra   Raposo, Catarina   Groß, Catharina   Wiendl, Heinz   Klotz, Luisa   

              Session Name:S16: MS Clinical Trials and Therapeutics  

              Topic:MS and Inflammatory Disease  

              Program Number:S16.003  

              Author Institution:Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Westfälische-Wilhelms-University Münster, Münster, Germany, Munster, Germany  F. Hoffmann-La Roche Ltd, Basel, Switzerland, Basel, Switzerland  

              Identification of multiple sclerosis endophenotypes by high dimensional blood signatures associated with distinct disease trajectories

              Author:Gross, Catharina C   Schulte-Mecklenbeck, Andreas   Steinberg, Olga V   Wirth, Timo   Lauks, Sarah   Baranzini, Sergio E   Bittner, Stefan   Bellmann-Strobl, Judith   Bünger, Nora   Eilers, Eva   Eveslage, Maria   Fleischer, Vinzenz   Gisevius, Barbara   Groppa, Sergiu   Haas, Jürgen   Kerschensteiner, Martin   Kirstein, Lucienne   Korsukewitz, Catharina   Lohmann, Lisa   Lünemann, Jan   Lüssi, Felix   Meyer zu Hörste, Gerd   Motte, Jeremias   Ruck, Tobias   Schwab, Nicholas   Meuth, Sven G   Paul, Friedemann   Wildemann, Brigitte   Kümpfel, Tania   Gold, Ralf   Zipp, Frauke   Klotz, Luisa   Wiendl, Heinz   

              Session Name:P1: MS Biomarkers  

              Topic:MS and Inflammatory Disease  

              Program Number:P1.008  

              Author Institution:University Hospital Münster, Münster, Germany  University of California San Francisco, San Francisco, CA  University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany  Max Delbrueck Center for Molecular Medicine and Charité Universitätsmedizin Berlin, Berlin, Germany  University of Münster, Münster, Germany  University Hospital Bochum, Bochum, Germany  University of Heidelberg, Heidelberg, Germany  Ludwig Maximilians University of Munich, Munich, Germany  University and University Hospital of Münster, Münster, Germany  Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany  Charite Universitatsmedizin in Berlin, Berlin, Germany  University Hospital Heidelberg, Heidelberg, Germany