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Pdgfrα-dependent Polr3b Exon Loss Recapitulates POLR3-related Hypomyelinating Leukodystrophy Phenotypes in vivo

Author:Michell-Robinson, Mackenzie A.   Watt, Kristin EN   Grouza, Vladimir   Macintosh, Julia   Pinard, Maxime   Tuznik, Marius   Chen, Xiaoru   Darbelli, Lama   Wu, Chia-Lun   Perrier, Stefanie   Chitsaz, Daryan   Uccelli, Nonthue A   Liu, Hanwen   Cox, Timothy   Mueller, Christoph W   Kennedy, Timothy E   Coulombe, Benoit   Rudko, David   Trainor, Paul A   Bernard, Geneviève   

Session Name:S2: Child Neurology and Developmental Neurology 1  

Topic:Child Neurology and Developmental Neurology  

Program Number:S2.004  

Author Institution:Research Institute of the McGill University Health Centre, Montreal, QC, Canada  Stowers Institute for Medical Research, Kansas City, MO  McConnell Brain Imaging Centre, Montreal, QC, Canada  Montreal Clinical Research Institute, Montreal, QC, Canada  Montreal Neurological Institute, Montreal, QC, Canada  School of Medicine, University of Missouri - Kansas City, Kansas City, MO  European Molecular Biology Laboratory, Heidelberg, Germany  

Decreased RNA polymerase III Expression Leads to Several Defects in Oligodendrocyte-Lineage Development

Author:Macintosh, Julia   Michell-Robinson, Mackenzie A.   Chen, Xiaoru   Bernard, Geneviève   

Session Name:P12: Child Neurology and Developmental Neurology: Autoimmune Encephalitides/Demyelinating Disorders/Infections  

Topic:Child Neurology and Developmental Neurology  

Program Number:P12.009  

Author Institution:McGill University, Montréal, QC, Canada  Mcgill University, Montreal, QC, Canada