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PRAX-562 is a Well-Tolerated, Novel Persistent Sodium Channel Blocker with Broad Anticonvulsant Activity in Multiple DEE Mouse Models

Author:Anderson, Lyndsey   Jancovski, Nikola   Eckert, William   Baker, Erin   Wagley, Pravin   Maljevic, Snezana   Reid, Christopher   Patel, Manoj   Kearney, Jennifer   Kahlig, Kristopher   Petrou, Steven   

Session Name:S34: Child Neurology and Developmental Neurology 2  

Topic:Child Neurology and Developmental Neurology  

Program Number:S34.007  

Author Institution:Praxis Precision Medicines, Boston, MA  Florey Institute of Neuroscience and Mental Health, Parkville, Australia  Northwestern University Feinberg School of Medicine, Chicago, IL  University of Virginia Health System, Charlottesville, VA  

PRAX-628 is a Novel, Well-Tolerated, Activity Dependent Sodium Channel Blocker with Potent Anticonvulsant Activity

Author:Eckert, William   Kahlig, Kristopher   Anderson, Lyndsey   Petrou, Steven   

Session Name:P4: Child Neurology and Developmental Neurology: Seizures 2  

Topic:Child Neurology and Developmental Neurology  

Program Number:P4.012  

Author Institution:Praxis Precision Medicines, Boston, MA  

PRAX-628: A Novel Sodium Channel Blocker with Greater Potency and Activity Dependence Compared to Standard of Care

Author:Kahlig, Kristopher   Chapman, Mark   Petrou, Steven   

Session Name:P8: Child Neurology and Developmental Neurology: Seizures 3  

Topic:Child Neurology and Developmental Neurology  

Program Number:P8.012  

Author Institution:Praxis Precision Medicines, Boston, MA  Icagen Ion Channel Technology, Durham, NC