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Effect of RIPK1 Inhibitor, SAR443820, on Serum Neurofilament Light Levels in Patients with Multiple Sclerosis: A Phase 2 Trial Design

Author:Montalban, Xavier   Kuhle, Jens   Fox, Robert   Vartanian, Timothy   Horakova, Dana   Filippi, Massimo   Roos, Ernest   Wallstroem, Erik   Atassi, Nazem   

Session Name:P6: MS Clinical Trials  

Topic:MS and Inflammatory Disease  

Program Number:P6.011  

Author Institution:Multiple Sclerosis Centre of Catalonia, Department of Neurology–Neuroimmunology, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain  Department of Neurology, University Hospital and University of Basel, Basel, Switzerland  Mellen Center for Multiple Sclerosis, Neurological Institute, Cleveland Clinic, Cleveland, OH  Brain and Mind Research Institute, Weill Cornell Medicine, Cornell University, New York, NY  Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University, Prague, Czech Republic  Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy  Sanofi, Bridgewater, NJ  Sanofi, Cambridge, MA