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Comparison of Efficacy Outcomes with Vutrisiran vs. Patisiran in hATTR Amyloidosis with Polyneuropathy: Post-hoc Analysis of the HELIOS-A Study

Author:Polydefkis, Michael   Birklein, Frank   Sekijima, Yoshiki   Pareyson, Davide   Waddington Cruz, Marcia   Danese, David   Capocelli, Kelley   Merkel, Madeline   Chen, Chongshu   Vest, John   Adams, David   

Session Name:S14: General Neurology: Emerging Therapies  

Topic:General Neurology  

Program Number:S14.003  

Author Institution:Johns Hopkins University School of Medicine, Baltimore, MD  Clinic and Polyclinic for Neurology, Johannes Gutenberg University of Mainz, Mainz, Germany  Shinshu University School of Medicine, Matsumoto, Japan  Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy  Clementino Fraga Filho University Hospital, Rio De Janeiro, Brazil  Alnylam Pharmaceuticals, Cambridge, MA  APHP, Le Kremlin-Bicetre Cedex, France  

Effect of Patisiran on Polyneuropathy and Cardiomyopathy in Patients with hATTR Amyloidosis with V122I/T60A Variants: A Phase 4 Observational Study

Author:Comenzo, Raymond L.   Shu, Francy   Malhotra, Saurabh   Hussain, Yessar   Zolty, Ronald   Desai, Urvi   Fernandez, Joel   Yureneva, Elena   Chou, Lin-Na   Capocelli, Kelley   

Session Name:S14: General Neurology: Emerging Therapies  

Topic:General Neurology  

Program Number:S14.005  

Author Institution:Tufts Medical Center, Boston, MA  UCLA Medical Center, Los Angeles, CA  Cook County Health, Chicago, IL  Austin Neuromuscular Center, Austin, TX  University of Nebraska Medical Center, Omaha, NE  Carolinas Healthcare System, Charlotte, NC  Morsani College of Medicine, Tampa, FL  Alnylam Pharmaceuticals, Cambridge, MA