Long-Term Safety and Efficacy of Azetukalner (XEN1101), a Novel, Potent KV7 Potassium Channel Opener in Adults With Focal Epilepsy: Update From the Ongoing 7-Year Open-Label Extension of X-TOLE

Safety and Effectiveness of Fenfluramine for the Treatment of Seizures in Lennox-Gastaut Syndrome: Results From the Final Analysis of an Open-Label Extension Study

Author:Knupp, Kelly   Scheffer, Ingrid   Ceulemans, Berten   Sullivan, Joseph   Nickels, Katherine   Lagae, Lieven   Guerrini, Renzo   Zuberi, Sameer   Nabbout, Rima   Riney, Kate   Lock, Michael   Dai, David   Davis, Ronald   Morita, Diego   Lothe, Amélie   Langlois, Mélanie   Zhang-Roper, Re   

Session Name:P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P8.002  

Author Institution:Children's Hospital Colorado, Aurora, CO  University of Melbourne, Austin Hospital and Royal Children's Hospital, Florey and Murdoch Children’s Research Institutes, Melbourne, Australia  Antwerp University Hospital, Antwerp, Belgium  University of California San Francisco Weill Institute for Neurosciences, Benioff Children’s Hospital, San Francisco, CA  Mayo Clinic, Rochester, MN  Member of the European Reference Network EpiCARE, University of Leuven, Leuven, Belgium  Meyer Children’s Hospital IRCCS, and University of Florence, Florence, Italy  Paediatric Neurosciences Research Group, Royal Hospital for Children, Glasgow, United Kingdom  Member of European Reference Network EpiCARE, Reference Centre for Rare Epilepsies, Necker Enfants Malades Hospital, APHP, U 1163 Institut Imagine, Université Paris Cité, Paris, France  The University of Queensland, St Lucia  Queensland Children's Hospital, South Brisbane, Australia  Independent Statistical Consultant, Haiku, HI  Syneos Health, Morrisville, NC  Neurology and Epilepsy Research Center, Orlando, FL  UCB, Brussels, Belgium  Hospital Ruber Internacional, Madrid, Spain  

Time to Prerandomization Seizure Count Design Sufficiently Assessed the Safety and Tolerability of Perampanel for the Treatment of Focal Seizures