Efficacy of Azetukalner in Focal Onset Seizure (FOS) Subtypes: Results From the Double-Blind, Placebo Controlled X-TOLE Study

A Stratified Analysis of Efficacy and Safety of Fenfluramine in Patients With Dravet Syndrome

Author:Nabbout, Rima   Sullivan, Joseph   Auvin, Stéphane   Ceulemans, Berten   Cross, J Helen   Devinsky, Orrin   Gil-Nagel, Antonio   Guerrini, Renzo   Knupp, Kelly   Perry, M Scott   Sanchez-Carpintero, Rocio   Scheffer, Ingrid   Specchio, Nicola   Strzelczyk, Adam   Wheless, James   Wirr,   

Session Name:P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P8.014  

Author Institution:Member of European Reference Network EpiCARE, Reference Centre for Rare Epilepsies, Necker Enfants Malades Hospital, APHP, U 1163 Institut Imagine, Université Paris Cité, Paris, France  University of California San Francisco Weill Institute for Neurosciences, Benioff Children’s Hospital, San Francisco, CA  Service de Neurologie Pédiatrique & INSERM U1141, Robert Debré University Hospital, APHP, Paris, France  University of Antwerp, Antwerp University Hospital, Antwerp, Belgium  UCL NIHR BRC Great Ormond Street Institute of Child Health, Great Ormond Street Hospital, London, United Kingdom  Comprehensive Epilepsy Center, NYU Langone Medical Center, New York, NY  Hospital Ruber Internacional, Madrid, Spain  Meyer Children’s Hospital IRCCS, University of Florence, Florence, Italy  Children's Hospital Colorado, Anschutz Medical Campus, Aurora, CO  Cook Children’s Medical Center, Fort Worth, TX  Clinica Universidad de Navarra, Pediatric Neurology Unit, Pamplona, Spain  University of Melbourne, Austin Hospital and Royal Children’s Hospital, Florey and Murdoch Children’s Research Institutes, Melbourne, Australia  Member of European Reference Network EpiCARE, Bambino Gesú Children’s Hospital, IRCCS , Rome, Italy  Goethe University Frankfurt, Epilepsy Center Frankfurt Rhine-Main & University Hospital Frankfurt, Frankfurt am Main, Germany  University of Tennessee Health Science Center & Le Bonheur Children’s Hospital, Memphis, TN  Mayo Clinic/Dept of Child Neurology, Rochester, MN  UCB, Brussels, Belgium  Member of the European Reference Network EpiCARE, University of Leuven, Leuven, Belgium  

Impact of Fenfluramine on Convulsive Seizure Frequency in Dose-Capped Patients With Dravet Syndrome

Author:Nabbout, Rima   Knupp, Kelly   Lagae, Lieven   Cross, J Helen   Sullivan, Joseph   Gil-Nagel, Antonio   Guerrini, Renzo   Strzelczyk, Adam   Langlois, Mélanie   Healy, Patrick   Lothe, Amélie   Scheffer, Ingrid   

Session Name:P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P8.015  

Author Institution:Member of the European Reference Network EpiCARE, Reference Centre for Rare Epilepsies, Hôpital Universitaire Necker-Enfants Malades, APHP, Institut Imagine, Université Paris Cité, Paris, France  University of Colorado, Children's Hospital Colorado, Aurora, CO  Member of the European Reference Network EpiCARE  University of Leuven, Leuven, Belgium  UCL NIHR BRC Great Ormond Street Institute of Child Health, Great Ormond Street Hospital, London, United Kingdom  University of California San Francisco Weill Institute for Neurosciences, Benioff Children’s Hospital, San Francisco, CA  Hospital Ruber Internacional, Madrid, Spain  IRCCS Fondazione Stella Maris, Pisa  Pediatric Neurology and Neurogenetics Unit, Anna Meyer Children’s Hospital, University of Florence, Florence, Italy  Goethe University Frankfurt, Epilepsy Center Frankfurt Rhine-Main & University Hospital Frankfurt, Frankfurt am Main, Germany  UCB, Brussels, Belgium  University of Melbourne, Austin Hospital and Royal Children’s Hospital, Florey and Murdoch Children’s Research Institutes, Melbourne, Australia