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Next Generation Prodrug Troriluzole: Increased Bioavailability of Riluzole with No Food Effect in Healthy Subjects

Author:Sevinsky, Heather   Rozakis, Rachel   Nepomuceno, Tracy   Malatesta, Jo Ann   Awsare, Bharat   Ashbrenner, Eric   Kaplita, Stephen   Gentile, Kimberly   Hussey, Elizabeth   Qureshi, Irfan   Coric, Vladimir   Bertz, Richard   

Session Name:S5: ALS and CMT: New Therapeutic Approaches  

Topic:Neuromuscular and Clinical Neurophysiology (EMG)  

Program Number:S5.006  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven , CT  Allucent, Cary, NC  Biohaven Pharmaceuticals, Inc, New Haven, CT  Certara, Inc, Princeton, NJ  Biohaven Pharmaceuticals, Inc, New Haven, CT  Biohaven Pharmaceuticals, Inc, Cheshire, CT  

Troriluzole Exhibits Favorable Hepatic Safety Profile Across a Diverse Range of Disorders

Author:Qureshi, Irfan   Beiner, Melissa   Bertz, Richard   Kaplita, Stephen   Yang, Rong   Munivar, Azim   Stock, David   Wirtz, Victoria   Coric, Vladimir   

Session Name:P4: General Neurology: Neuroimmunology  

Topic:General Neurology  

Program Number:P4.013  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  

No Clinically Relevant Effects of Hepatic Impairment on the Pharmacokinetics of a Next Generation Prodrug Troriluzole

Author:Bertz, Richard   Rozakis, Rachel   Donohue, Mary   Sevinsky, Heather   Awsare, Bharat   Kaplita, Stephen   Hussey, Elizabeth   Qureshi, Irfan   Coric, Vladimir   

Session Name:P4: General Neurology: Neuroimmunology  

Topic:General Neurology  

Program Number:P4.014  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  Allucent, Cary, NC