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Population Pharmacokinetic Modeling of Riluzole After Administration of a Next Generation Prodrug Troriluzole

Author:Bertz, Richard   Pene Dumitrescu, Teodora   Wu, Yi Shuan   Jeong, Angela   Sevinsky, Heather   Qureshi, Irfan   Coric, Vladimir   

Session Name:S3: Contemporary Neurology Practice and Emerging Neurologic Therapies  

Topic:General Neurology  

Program Number:S3.007  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  Allucent, Quakertown, PA  Allucent, Cary, NC  

Next Generation Prodrug Troriluzole: Increased Bioavailability of Riluzole with No Food Effect in Healthy Subjects

Author:Sevinsky, Heather   Rozakis, Rachel   Nepomuceno, Tracy   Malatesta, Jo Ann   Awsare, Bharat   Ashbrenner, Eric   Kaplita, Stephen   Gentile, Kimberly   Hussey, Elizabeth   Qureshi, Irfan   Coric, Vladimir   Bertz, Richard   

Session Name:S5: ALS and CMT: New Therapeutic Approaches  

Topic:Neuromuscular and Clinical Neurophysiology (EMG)  

Program Number:S5.006  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven , CT  Allucent, Cary, NC  Biohaven Pharmaceuticals, Inc, New Haven, CT  Certara, Inc, Princeton, NJ  Biohaven Pharmaceuticals, Inc, New Haven, CT  Biohaven Pharmaceuticals, Inc, Cheshire, CT  

Safety, Tolerability, and Pharmacokinetics of Single and Multiple Rising Doses of a Next Generation Prodrug Troriluzole in Healthy Subjects

Author:Sevinsky, Heather   Awsare, Bharat   Rozakis, Rachel   Gentile, Kimberly   Mydlow, Patricia   Ashbrenner, Eric   Ham, Rachel   Stock, David   Qureshi, Irfan   Coric, Vladimir   Bertz, Richard   

Session Name:P4: General Neurology: Neuroimmunology  

Topic:General Neurology  

Program Number:P4.012  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  Allucent, Cary, NC  

Troriluzole Exhibits Favorable Hepatic Safety Profile Across a Diverse Range of Disorders

Author:Qureshi, Irfan   Beiner, Melissa   Bertz, Richard   Kaplita, Stephen   Yang, Rong   Munivar, Azim   Stock, David   Wirtz, Victoria   Coric, Vladimir   

Session Name:P4: General Neurology: Neuroimmunology  

Topic:General Neurology  

Program Number:P4.013  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  

No Clinically Relevant Effects of Hepatic Impairment on the Pharmacokinetics of a Next Generation Prodrug Troriluzole

Author:Bertz, Richard   Rozakis, Rachel   Donohue, Mary   Sevinsky, Heather   Awsare, Bharat   Kaplita, Stephen   Hussey, Elizabeth   Qureshi, Irfan   Coric, Vladimir   

Session Name:P4: General Neurology: Neuroimmunology  

Topic:General Neurology  

Program Number:P4.014  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  Allucent, Cary, NC