Migraine is a neurological disabling condition which is prevalent globally and it is a major reason sought for the medical care. A large number of population evidenced by 1 billion people around the world are affected due to migraine disorder. It is the sixth most disabling illness in the world and fifth leading cause of year of life lived with disability in south Asia. This study is conducted in order to explore the clinical and functional disability of patient with migraine among Nepali residents.

Quantitative research methods were used to carry out this study. MIDAS questionnaire was used. Data was collected under Likert scale format. Data were analyzed by using descriptive statistical method by SPSS (version 20).

About 219 patients were diagnosed with migraine in the period of 3 months. Majority of participants were in the age group of 20-29 years (29.7%) followed by age group of 30-39(27.9%) with the majority of female participants (79%).

The various symptoms experienced by participants were throbbing pain (87.2%), photophobia (9.2%), Phonophobia (86.3%), Nausea (54.3%) and vomiting (38.8%). About 36.52% of patients were in the category of episodic migraine and 63.47% were in the category of chronic migraine. Most of the subjects (84.5%) experienced the severe level of functional disability.

It is concluded that chronic migraine was found to be 3.4 times higher in disability called as level IV in comparison with level I also called as lower disability level and this relationship was statistically significant (OR=3.4, 95%CI=1.01-11.48).