A Pilot Study of Free and Cued Selective Reminding Test in a Lebanese Sample: A study on Normal, MCI and AD patients
Maryse Hayek1, Wassim Najjar2, Patricia Fadel1, Tatiana Abou-Mrad3, Gordon Chelune4, Lubna Tarabey5, Fadi Abou-Mrad5
1Faculty of Medical Sciences, Lebanese University, Lebanon; Memory Clinic, Division of Neurology, Saint Charles Hospital, Lebanon; Faculty of Medicine, St Joseph University (USJ), Lebanon; Lebanon Memory Group for Clinical Research (GMRC-Liban), Lebanon, 2Faculty of Medicine, University of Balamand, Lebanon, 3Faculty of Medicine, American University of Beirut, Lebanon, 4Center for Alzheimer’s Care, Imaging and Research, University of Utah, Salt Lake City, USA, 5Faculty of Medical Sciences, Lebanese University, Lebanon; Memory Clinic, Division of Neurology, Saint Charles Hospital, Lebanon; Lebanon Memory Group for Clinical Research (GMRC-Liban), Lebanon
Objective:
Our aim was to assess the suitability of the use of a culturally adapted version of the FCSRT in the Lebanese population diagnosed with MCI and AD through comparing between three groups of subjects – normal, MCI and AD.
Background:
The Free and Cued Selective Reminding Test (FCSRT) is a memory test that assesses learning and acquisition, by providing category cues in the learning process. It is a reliable tool for the assessment of episodic memory, used to differentiate between Alzheimer Disease (AD) patients and patients with Mild Cognitive Impairment (MCI).
Design/Methods:
Subjects were recruited based on their visit, for a regular memory consultation in a memory clinic in Beirut. All of them completed the test conducted by a clinician.
Results:
Results: The sample included 3 populations divided as follows: 29 normal, 22 MCI and 24 AD subjects. Our results showed that the adapted Arabic version of the FCSRT is discriminating between the 3 populations with a major significant difference between the healthy and AD population. The overall profile on the FCSRT revealed that normal subjects had the highest scores followed by MCI and then AD subjects. The learning curve of normal controls and MCI patients is ascendant while AD subjects exhibit a depressed learning curve.
Conclusions:
This study represents a novel contribution regarding the adequacy of the Arabic version of the FCSRT in terms of distinguishing between AD and non-AD subjects. Besides, it gives new possibilities concerning the use of the FCSRT in the evaluation of the spectrum of memory disorders.