### 4520

Regularization of Digitally Integrated, Inductive k-Space Trajectory Measures
Jan Ole Pedersen1,2,3, Christian G. Hanson4, Rong Xue5,6, and Lars G. Hanson7,8

1Danish Research Centre for Magnetic Resonance, Hvidovre, Denmark, 2Sino-Danish Center for Education and Research, Aarhus, Denmark, 3Philips Healthcare, København SV, Denmark, 4Denmark, 5Chinese Academy of Sciences, State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Beijing, China, 6University of Chinese Academy of Sciences, Sino-Danish College, Beijing, China, 7Department of Electrical Engineering, Technical University of Denmark, Center for Magnetic Resonance, Kgs Lyngby, Denmark, 8Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Danish Research Centre for Magnetic Resonance, Hvidovre, Denmark

### Synopsis

Determining k-space trajectories inductively is conceptually simple, but rely on integration of the induced signal. Performing this integration digitally allow for higher degree of flexibility than analog integration, which is necessary to account for, e.g., refocusing RF pulses. Digital integration, however, require high bandwidth sampling of the induced signal as digitization error accumulate, making the overall approach less attractive. We show that the necessary bandwidth can be reduced by performing regularization using a gradient coil current measure.

### Methods

The k-space location is given by

$$k_r(t) = \gamma\int_0^t G_r(\tau)\, d\tau$$,

where $k_r(t) = 0$ at $t=0$, and $G_r(t)$ is the gradient in direction $r$. An inductive gradient measure was obtained by placing a pick-up coil (20 windings, Ø3cm) in a gradient field and summing discrete samples of the generated voltage, $v_r(t)$:

$$G_r^v(t) = \sum_{i=1}^N b_1v_r(\tau_i) \Delta t + c$$.

In this sum over $N=(t-t_1)/\Delta t$ samples, $b_1$ is a constant depending on the position and geometry of the pick-up coil, $t_1$ is the time point of the first sample where $\Delta t$ is the sampling dwell time, $\tau_i = (t_1 + i \Delta t)$, and $c$ is a constant accounting for any gradient applied at $t=0$. A simple, regularized, inductive measure of the gradient field can then be obtained as

$$G_r^M(t) = \sum_{i=1}^N [b_1 v_r(\tau_1) \Delta t - R(i)]+ c$$,

with a regularization term:

$$R(i) = \eta[G_r^M(\tau_{i-1} - b_2 I(\tau_{i-1}) ]^2$$,

$b_2$ is a predetermined scaling factor, and $\eta$ ensures the correct sign of $R(i)$, so that $G_r^M(t)$ is relatively slowly pulled towards the current-based gradient measure,$b_2 I(t)$. A measure of $G_r^M(t)$ was in near real-time generated by custom open-source circuitry[3] that features ADCs sampling $v_r(t)$ and $I(t)$ (16-bit@200kS/s). The gradient measure was used for phase modulation of a carrier signal at the Larmor frequency, which was transmitted to a single receive channel of a 3T Achieva system (Philips, Best, The Netherlands). This allows for determining the k-space trajectory from the accumulated phase of the scanner-acquired signal, while the remaining receive channels concurrently acquire the MR signal.

### Results

Examples of reconstructed echo-planar imaging data is shown in figure 1. EPI was chosen sincethe well-known ghosting artefact is directly caused by k-space trajectory errors in direction of the readout gradient. An example of reconstructed spiral data is shown in figure 3. Duyn’s method [4] was used to obtain k-space trajectories used as ground truth, and the difference to images reconstructed using this is shown in figure 2 and 4.

### Discussion

The regularized, inductive k-space trajectory measure outperformed measures that were only inductive or current-based, and yielded reconstructed images without visible artefacts. The method does not rely on a LTI behavior of the gradients (as required by Duyn’s method), as it facilitates concurrent acquisition of MR data and k-space trajectories, as field probes also do. While field probes yield better sensitivity, the presented method is inexpensive, insensitive to field inhomogeneity and is independent of spin history.

### Conclusion

The presented method is a good candidate for inexpensive and relatively simple real-time determination of k-space trajectories, applicable for debugging and for corrected reconstruction of gradient-demanding and non-Cartesian sequences. In its current implementation, each gradient direction needs to be measured separately, however. The method allows concurrent MRI acquisition, and is applicable to situations that are challenging for other techniques, e.g., for strong $B_0$ inhomogeneity, or when LTI-behavior of the gradient system cannot be assumed.

### Acknowledgements

No acknowledgement found.

### References

[1] Senaj V et al. Inductive measurement of magnetic field gradients for magnetic resonance imaging. Rev. Sci. Instrum., 69(6):2400-2405 (1998)

[2] Spielman DM and Pauly JM. Spiral imaging on a small-bore system at 4.7T. Magn. Reson. Med., 34(4):580-585, (1995)

[3] Pedersen J et al. General purpose electronics for real-time processing and encoding of non-MR data in MR acquisitions. Concepts Magn. Reson. Part B Magn. Reson. Eng, e21385 (2018)

[4] Duyn J et al. Simple Correction Method for k-Space Trajectory Deviations in MRI, J. Magn. Reson., 132, 150-153 (1998)

### Figures

Reconstructed EPI data using k-space trajectories based on [left] solely a digitally integrated inductive measure ($G_r^v(t)$), [mid] scaling of a gradient coil current measure ($b_2 I(t))$, and [right] a measure obtained by regularizing the inductive measure by the current-based measure ($G_r^M(t)$).

Equally scaled differences between the images presented in figure 1, and a reference image reconstructed using a k-space trajectory obtained using Duyn's method.

Reconstructed spiral data, using the [left] regularized, inductive k-space trajectory measure ($G_r^M(t)$), and [right] the nominal k-space trajectory.

Equally scaled differences between the images presented in figure 3, and a reference image reconstructed using a k-space trajectory obtained using Duyn's method.

Proc. Intl. Soc. Mag. Reson. Med. 27 (2019)
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