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Upstream Versus Downstream Complement Blockade: Potential Mechanistic Advantages of aC1s Targeting in Myasthenia Gravis

Author:Shahar Shelly  Marianna Lalla  Yang Zhao  Linda Rehaume  Jennifer Cross  Tuan Vu  

Topic:Autoimmune Neurology  

Program Number:P1.058  

Author Institution:Rambam Medical Center, Haifa, Israel  Dianthus Therapeutics, London, United Kingdom  Dianthus Therapeutics, Waltham, MA  Dianthus Therapeutics, New York, NY  Dianthus Therapeutics, Port Coquitlam, BC, Canada  University of South Florida, Tampa, FL  

Minimal Symptom Expression with Claseprubart, an Active C1S Inhibitor, in Patients with Generalized Myasthenia Gravis

Author:Said Beydoun  Nils Erik Gilhus  Amit Sachdev  Maria Ait-Tihyaty  Caitlin Briggs  Uzma Siddiqui  Luke Hickey  Marianna Lalla  Marek Smilowski  

Topic:Autoimmune Neurology  

Program Number:P2.008  

Author Institution:University of Southern California Healthcare Consultation Center 2, Los Angeles, CA  Haukeland University Hospital, Bergen, Norway  Michigan State University, East Lansing, MIDianthus Therapeutics, Raleigh, NC  Dianthus Therapeutics, Amherst, NY  Dianthus Therapeutics, King Of Prussia, PA  Dianthus Therapeutics, London, United Kingdom  Neurologia Slaska Centrum Medyczne, Katowice, Poland