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Safety and ARIA Analyses of Oral Anti-amyloid Oligomer Agent Valiltramiprosate in APOE4/4 Homozygotes with Early Alzheimer’s Disease (AD): Results of the Phase 3 78-week APOLLOE4 Trial

Author:Liang, Earvin   Cohen, Sharon   Sabbagh, Marwan   Watson, David   Abushakra, Susan   Barakos, Jerome   Kesslak, J Patrick   MacSweeney, Emer   Bennys, Karim   Boada, Merce   McLaine, Rosalind   Flint, Susan   Power, Aidan   Hey, John A   Tolar, Martin   

Session Name:S1: New Perspectives on Alzheimer's Therapeutics  

Topic:Aging, Dementia, and Behavioral Neurology  

Program Number:S1.009  

Author Institution:Alzheon Inc, MA  Toronto Memory Program, Toronto, ON, Canada  Barrow Neurological Institute, Phoenix, AZ  Alzheimer’s Research and Treatment Center, Wellington, FL  Clario Inc, PA  Re:Cognition Health, United Kingdom  University of Montpellier, France  Ace Alzheimer Center, Spain  Alzheon Inc., East Haven, CT  Alzheon, Framingham, MA  

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Effects of Oral Valiltramiprosate on Clinical Efficacy, Safety, and Brain Volume Outcomes in APOE4/4 Homozygotes with Early Alzheimer’s Disease (AD): Topline Results of the 78-week Phase 3 APOLLOE4 Trial

Author:Abushakra, Susan   Cohen, Sharon   Sabbagh, Marwan   Watson, David   Power, Aidan   Porsteinsson, Anton   MacSweeney, Emer   Boada, Merce   Ousset, Pierre Jean   Liang, Earvin   Flint, Susan   Kesslak, J. Patrick   Albayrak, Adem   Bray, Margaret   Hey, John A.   Tolar, Martin   

Session Name:P1: Aging, Dementia, and Behavioral Neurology: Alzheimer's Disease and Anti-amyloid Therapies 1  

Topic:Aging, Dementia, and Behavioral Neurology  

Program Number:P1.001  

Author Institution:Alzheon, Inc., Framingham, MA  Toronto Memory Program, Toronto, ON, Canada  Barrow Neurological Institute, Phoenix, AZ  Alzheimer’s Research and Treatment Center, Wellington, FL  University of Rochester School of Medicine, Rochester, NY  Re:Cognition Health, London, United Kingdom  Ace Alzheimer Center, Barcelona, Barcelona, Spain  Toulouse Gerontopole & Alzheimer’s Clinical Research Center, Toulouse, France  Alzheon, Framingham, MA  

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Correlations between Clinical and Brain Volume Effects of Oral Valiltramiprosate in APOE4/4 Homozygotes with MCI: Pre-specified Analyses of the Phase-3 APOLLOE4 78-Week Trial in APOE4/4 Homozygotes with Early Alzheimer’s Disease (AD)

Author:Sabbagh, Marwan   Abushakra, Susan   Tosun, Duygu   Watson, David   Power, Aidan   Liang, Earvin   MacSweeney, Emer   Boada, Merce   Bennys, Karim   Matias-Guiu, Jorge   Hey, John A.   Flint, Susan   Kesslak, J. Patrick   Bracoud, Luc   Bray, Margaret   Tolar, Martin   

Session Name:P6: Aging, Dementia, and Behavioral Neurology: Alzheimer's Disease: Beyond Anti-amyloid Therapeutics 3  

Topic:Aging, Dementia, and Behavioral Neurology  

Program Number:P6.010  

Author Institution:Barrow Neurological Institute, Phoenix, AZ  Alzheon, Inc., Framingham, MA  University of California San Francisc, CA  Alzheimer’s Research and Treatment Center, Wellington, FL  Re:Cognition Health, London, United Kingdom  International University of Catalunya, Barcelona, Spain  Hopital Gui de Chauliac - CHRU de Montpellier, Montpellier, France  Hospital Clinico San Carlos, Madrid, Spain  Clario, Inc., Philadelphia, PA  

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