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Treatment Effect of Idebenone in Leber Hereditary Optic Neuropathy Using an Alternate Threshold of Clinically Relevant Visual Acuity Change

Author:Subramanian, Prem   Yu-Wai-Man, Patrick   Carelli, Valerio   Llòria, Xavier   Klopstock, Thomas   

Session Name:S18: Neuro-ophthalmology/Neuro-otology  

Topic:Neuro-ophthalmology/Neuro-otology  

Program Number:S18.002  

Author Institution:Sue Anschutz-Rodgers University of Colorado Eye Center, Aurora, CO  University of Cambridge, United Kingdom  IRCCS Istituto di Scienze Neurologiche di Bologna, Bologna, Italy  Chiesi Farmaceutici S.p.A, Parma, Italy  Friedrich Baur Institute, Munich, Germany  

Lenadogene Nolparvovec Gene Therapy for Leber Hereditary Optic Neuropathy in the Real-life Setting

Author:Newman, Nancy   Vignal-Clermont, Catherine   La Morgia, Chiara   Carelli, Valerio   Yu-Wai-Man, Patrick   Moster, Mark   Sergott, Robert   Thornton, Sarah   Taiel, Magali   Sahel, José-Alain   

Session Name:S18: Neuro-ophthalmology/Neuro-otology  

Topic:Neuro-ophthalmology/Neuro-otology  

Program Number:S18.003  

Author Institution:Emory University School of Medicine, Atlanta, GA  Hopital Fondation A de Rothschild, Paris, France  University of Bologna, Bologna, Italy  John van Geest Centre for Brain Repair and MRC Mitochondrial Biology Unit, Department of Clinical Neurosciences, University of Cambridge, Newcastle Upon Tyne, United Kingdom  Neuro-Ophthalmology -Wills Eye Hospital, Philadelphia, PA  Wills Eye Hospital, Philadelphia, PA  Wills Eye Hospital, PA  GenSight Biologics, Paris, France  Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France  

Efficacy of Lenadogene Nolparvovec Gene Therapy Versus Idebenone: A Matched Adjusted Indirect Comparison

Author:Biousse, Valerie   Yu-Wai-Man, Patrick   Newman, Nancy   Carelli, Valerio   Pierache, Adeline   Montestruc, Francois   Taiel, Magali   Sahel, Jose-Alain   

Session Name:S18: Neuro-ophthalmology/Neuro-otology  

Topic:Neuro-ophthalmology/Neuro-otology  

Program Number:S18.004  

Author Institution:Emory University School of Medicine, Atlanta, GA  John van Geest Centre for Brain Repair and MRC Mitochondrial Biology Unit, Department of Clinical Neurosciences, University of Cambridge, Newcastle Upon Tyne, United Kingdom  University of Bologna, Bologna, Italy  EXYSTAT, Malakoff, France  GenSight Biologics, Paris, France  Sorbonne Université, INSERM, CNRS, Institut de la Vision, France  

Longitudinal Disease Trajectories in Treatment-naïve Subacute/Dynamic Eyes With Leber Hereditary Optic Neuropathy From the Case Record Survey-Two

Author:Llòria, Xavier   Yu-Wai-Man, Patrick   van Everdingen, Judith   Krawczynski, Maciej   Carelli, Valerio   Klopstock, Thomas   

Session Name:P10: Neuro-ophthalmology/Neuro-otology: Artificial Intelligence and Genetics in Neuro-ophthalmology  

Topic:Neuro-ophthalmology/Neuro-otology  

Program Number:P10.010  

Author Institution:Chiesi Farmaceutici S.p.A, Italy  University of Cambridge, United Kingdom  The Rotterdam Eye Hospital, Rotterdam, Netherlands  Poznan University of Medical Sciences, Poznan, Poland  IRCCS Istituto di Scienze Neurologiche di Bologna, Bologna, Italy  Friedrich Baur Institute, Munich, Germany