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ORATORIO-HAND: Results of the Primary Analysis of Ocrelizumab vs Placebo in Primary Progressive Multiple Sclerosis, Including Older Patients and Those With More Advanced Disease

Author:Giovannoni, Gavin   Airas, Laura   Bove, Riley   Cutter, Gary   Hobart, Jeremy   Kuhle, Jens   Montalban, Xavier   Tur, Carmen   Wolinsky, Jerry   Schneble, Hans-Martin   Baldinotti, Anna   Bonati, Ulrike   Giacobino, Caroline   Wang, Qing   Yang, Ke   Oh, Jiwon   

Session Name:S40: Multiple Sclerosis: Clinical Trials/Science and Real-world Evidence  

Topic:Multiple Sclerosis  

Program Number:S40.001  

Author Institution:Department of Neurology, Royal London Hospital, Barts Health NHS Trust, London, UK and Blizard Institute, Queen Mary University, London, UK, London, United Kingdom  University of Turku, Turku, Finland, Turku, Finland  UCSF Weill Institute for Neuroscience, Department of Neurology, University of California San Francisco, San Francisco, CA, USA, CA  The University of Alabama at Birmingham, School of Public Health, Birmingham, AL, USA, Birmingham, AL  Peninsula Medical School, Plymouth University, UK, Plymouth, United Kingdom  MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland, Switzerland  Centre d'Esclerosi Múltiple de Catalunya, Vall d'Hebron University Hospital, Barcelona, Spain, Barcelona, Spain  Queen Square MS Centre, Department of Neuroinflammation, Institute of Neurology, Faculty of Brain Sciences, University College London (UCL), London, UK/Neurology-Neuroimmunology Department, Multiple Sclerosis Centre of Catalonia (CEMCAT), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain, Un  Department of Neurology, University of Texas Health Science Center, Houston, TX, USA, TX  F. Hoffmann-La Roche Ltd, Basel, Switzerland, Switzerland  F. Hoffmann-La Roche Ltd, Basel, Switzerland, Basel, Switzerland  Division of Neurology, Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada, ON, Canada  

Efficacy and Safety of Ocrelizumab Compared With Fingolimod in Pediatric-onset Relapsing-remitting MS: Results of the Phase III OPERETTA Two Study

Author:Banwell, Brenda   Kotulska, Katarzyna   Rostásy, Kevin   Deiva, Kumaran   Sato, Henry   Filippi, Massimo   Chitnis, Tanuja   Sormani, Maria Pia   Krupp, Lauren   Bar-Or, Amit   Evershed, Joanna   El Azzouzi, Bouchra   Wang, Qing   Lin, Chien-Ju   Hogea, Alexandra   Schneble, Hans-Martin   Manlius, Corinne   Waubant, Emmanuelle   

Session Name:S40: Multiple Sclerosis: Clinical Trials/Science and Real-world Evidence  

Topic:Multiple Sclerosis  

Program Number:S40.005  

Author Institution:Department of Pediatrics, Johns Hopkins University, Baltimore, MD, USA, Baltimore, MD  Department of Neurology and Epileptology, The Children’s Memorial Health Institute, Warsaw, Poland, Warsaw, Poland  Pediatric Neurology at Children's Hospital, Datteln, Germany, Datteln, Germany  Department of Pediatrics Neurology, Bicêtre Hospital, Le Kremlin-Bicêtre, France and Paris Sud-Saclay University, Le Kremlin-Bicêtre, France, Le Kremlin-Bicêtre, France  Neurological Institute of Curitiba, Curitiba, PR, Brazil, Curitiba, PR, Brazil  Neuroimaging Research Unit, Division of Neuroscience, Neurology Unit, Neurorehabilitation Unit and Neurophysiology Service, IRCCS San Raffaele Scientific Institute, and Vita-Salute San Raffaele University, Milan, Italy, Milan, Italy  Department of Pediatric Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA and Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, Boston, MA  DISSAL, University of Genoa, Genoa, Italy, Genoa, Italy  Department of Neurology, NYU Langone Health, New York, NY, USA, New York, NY  Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA  Roche Products Ltd, Welwyn Garden City, UK, Welwyn Garden City, United Kingdom  F. Hoffmann-La Roche Ltd, Basel, Switzerland, Basel, Switzerland  Neurology, University of California San Francisco, San Francisco, CA, USA, San Francisco, CA