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Humoral Vaccine Responses and One-year Follow-up of Infants Potentially Exposed to Ocrelizumab During Pregnancy and Breastfeeding: Final Analyses of the Prospective, Multicenter, Open-label, Phase IV Studies MINORE and SOPRANINO

Author:Dobson, Ruth   Bove, Riley   Hellwig, Kerstin   Oreja-Guevara, Celia   Derfuss, Tobias J.   Shah, Anna   Graham, Edith L.   McElrath, Thomas F.   Pietrasanta, Carlo   Maillart, Elisabeth   Jacobs, Dina   Kazlauskaite, Agne   Alves, Daniela   Raposo, Catarina   Craveiro, Licinio   Lin, Chien-Ju   Pasquarelli, Noemi   Vukusic, Sandra   

Session Name:S40: Multiple Sclerosis: Clinical Trials/Science and Real-world Evidence  

Topic:Multiple Sclerosis  

Program Number:S40.002  

Author Institution:Centre for Preventive Neurology, Wolfson Institute of Population Health, Queen Mary University of London, London, UK, London, United Kingdom  Department of Neurology, UCSF Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA, Berkeley, CA  Katholisches Klinikum Bochum, St. Josef Hospital, Universitätsklinikum, Bochum, Germany, Bochum, Germany  Neurology, Hospital Clínico San Carlos, IdISSC, Madrid, Spain, Madrid, Spain  University Hospital Basel, University of Basel, Basel, Switzerland, Basel, Switzerland  Rocky Mountain MS Center, Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA, Aurora, CO  Multiple Sclerosis and Neuroimmunology, Northwestern University, Chicago, IL, USA, Chicago, IL  Division of Maternal-Fetal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, Boston, MA  NICU, Department of Woman, Child and Newborn, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico and Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, Milan, Italy  Neurology Department, Hôpital de la Pitié Salpêtrière, Assistance Publique des Hôpitaux de Paris, Paris, France, Paris, France  Department of Neurology, Perelman School of Medicine at the Hospital of the University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA  F. Hoffmann-La Roche Ltd, Basel, Switzerland, Basel, Switzerland  Roche Products Ltd, Welwyn Garden City, UK, Welwyn Garden City, United Kingdom  Service de Neurologie et Sclérose en Plaques, Fondation Eugène Devic EDMUS contre la Sclérose en Plaques, Hôpital Neurologique Pierre Wertheimer, Lyon, France, BRON Cedex, France  

Predicting the First Attack: Comparison of 2023 Radiologically Isolated Syndrome and 2024 McDonald Criteria

Author:Gunduz, Tuncay   Emekli, Ahmed Serkan   Barburoglu, Mehmet   Ozakbas, Serkan   Piri Cinar, Bilge   Kaya, Ergi   Demir, Serkan   gungor dogan, ipek   Cetinkaya Tezer, Damla   Kocer, Belgin   Ercan, Merve Bahar   Tuncer, Asli   Karabudak, Rana   Acar Ozen, Nazire   Demirel, Ezgi   Cilingir, Vedat   Seferoglu, Meral   Ethemoglu, Ozlem   SIVACI, Ali   Omerhoca, Sami   Kale, Nilufer   Derle ciftci, Eda   Kilinc Toprak, Munire   Ugur, Ugurcan   Ocek, Levent   Ciftci Gedik, Irem   Uzunkopru, Cihat   Beckmann, Yesim   Gumus, Haluk   Sen, Sedat   Kurtuncu, Murat   

Session Name:S40: Multiple Sclerosis: Clinical Trials/Science and Real-world Evidence  

Topic:Multiple Sclerosis  

Program Number:S40.003  

Author Institution:Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey  Izmir University of Economics Medical Point Hospital, Izmir, Turkey  Faculty of Medicine, Samsun University, Samsun, Turkey  University of Health Sciences , Tepecik Training and Research Hospital, Izmir, Turkey  University of Health Sciences, Sancaktepe Sehit Prof Dr Ilhan Varank Training and Research Hospital, ISTANBUL, Turkey  Faculty of Medicine , Gazi University, Ankara, Turkey  School of Medicine, Hacettepe University, Ankara, Turkey  Academic Neurologist, Ankara, Turkey  Faculty of Medicine, Van Yuzuncu Yil University, Van, Turkey  Bursa Yüksek Ihtisas Education and Research Hospital, Turkey  Faculty of Medicine, Harran University , Sanliurfa, Turkey  University of Health Sciences Bagcilar Training and Research Hospital, Istanbul, Turkey  Faculty of Medicine, Baskent University, Ankara, Turkey  Health Sciences University Haydarpasa Numune Training and Research Hospital, Istanbul , Turkey  Katip Celebi University, Ataturk Training and Research Hospital, IZMIR, Turkey  Faculty of Medicine, Selcuk University, Konya, Turkey  Faculty of Medicine, Ondokuz Mayis University, Turkey  

Efficacy and Safety of Fenebrutinib vs Ocrelizumab in Primary Progressive Multiple Sclerosis: Primary Results of the Phase III FENtrepid Study

Author:Bar-Or, Amit   Oh, Jiwon   Giovannoni, Gavin   Sormani, Maria Pia   Weber, Martin S.   Stoll, Sharon   Nicholas, Jacqueline A.   Büdingen, H.-Christian von   Lopez, Jon   Roberts, Louise   Triyatni, Miriam   Qi, Qi   Ratchford, John N.   Napieralski, Julie   Goodyear, Alexandra   Hauser, Stephen L.   Kappos, Ludwig   

Session Name:S40: Multiple Sclerosis: Clinical Trials/Science and Real-world Evidence  

Topic:Multiple Sclerosis  

Program Number:S40.004  

Author Institution:Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA  St. Michael’s Hospital, University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada  Queen Mary University of London, London, UK, London, United Kingdom  University of Genoa, Genoa, Italy, Genoa, Italy  Institute of Neuropathology and Department of Neurology, University Medical Center and Fraunhofer Institute for Translational Medicine and Pharmacology, Göttingen, Germany, Göttingen, Germany  Advocare Stoll Medical Group, Philadelphia, PA, USA, Philadelphia, PA  OhioHealth Multiple Sclerosis Centre, Riverside Methodist Hospital, Columbus, OH, USA, Columbus, OH  F. Hoffmann-La Roche Ltd, Basel, Switzerland, Basel, Switzerland  Genentech, Inc., South San Francisco, CA, USA, South San Francisco, CA  University of California San Francisco, San Francisco, CA, USA, San Francisco, CA  University Hospital and University Basel, Research Center for Clinical Neuroimmunology and Neuroscience (RC2NB), Basel, Switzerland, Basel, Switzerland  

Efficacy and Safety of Ocrelizumab Compared With Fingolimod in Pediatric-onset Relapsing-remitting MS: Results of the Phase III OPERETTA Two Study

Author:Banwell, Brenda   Kotulska, Katarzyna   Rostásy, Kevin   Deiva, Kumaran   Sato, Henry   Filippi, Massimo   Chitnis, Tanuja   Sormani, Maria Pia   Krupp, Lauren   Bar-Or, Amit   Evershed, Joanna   El Azzouzi, Bouchra   Wang, Qing   Lin, Chien-Ju   Hogea, Alexandra   Schneble, Hans-Martin   Manlius, Corinne   Waubant, Emmanuelle   

Session Name:S40: Multiple Sclerosis: Clinical Trials/Science and Real-world Evidence  

Topic:Multiple Sclerosis  

Program Number:S40.005  

Author Institution:Department of Pediatrics, Johns Hopkins University, Baltimore, MD, USA, Baltimore, MD  Department of Neurology and Epileptology, The Children’s Memorial Health Institute, Warsaw, Poland, Warsaw, Poland  Pediatric Neurology at Children's Hospital, Datteln, Germany, Datteln, Germany  Department of Pediatrics Neurology, Bicêtre Hospital, Le Kremlin-Bicêtre, France and Paris Sud-Saclay University, Le Kremlin-Bicêtre, France, Le Kremlin-Bicêtre, France  Neurological Institute of Curitiba, Curitiba, PR, Brazil, Curitiba, PR, Brazil  Neuroimaging Research Unit, Division of Neuroscience, Neurology Unit, Neurorehabilitation Unit and Neurophysiology Service, IRCCS San Raffaele Scientific Institute, and Vita-Salute San Raffaele University, Milan, Italy, Milan, Italy  Department of Pediatric Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA and Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, Boston, MA  DISSAL, University of Genoa, Genoa, Italy, Genoa, Italy  Department of Neurology, NYU Langone Health, New York, NY, USA, New York, NY  Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA  Roche Products Ltd, Welwyn Garden City, UK, Welwyn Garden City, United Kingdom  F. Hoffmann-La Roche Ltd, Basel, Switzerland, Basel, Switzerland  Neurology, University of California San Francisco, San Francisco, CA, USA, San Francisco, CA  

Disentangling Age-related and Disease-specific Upper Cervical Cord Atrophy in Multiple Sclerosis

Author:Rocca, Maria   Jain, Kshiteeja   Storelli, Loredana   Valsasina, Paola   Preziosa, Paolo   Meani, Alessandro   Pantano, Patrizia   Piervincenzi, Claudia   Gallo, Antonio   d'Ambrosio, Alessandro   De Stefano, Nicola   Cortese, Rosa   Filippi, Massimo   

Session Name:S40: Multiple Sclerosis: Clinical Trials/Science and Real-world Evidence  

Topic:Multiple Sclerosis  

Program Number:S40.006  

Author Institution:IRCCS San Raffaele Scientific Institute, and Vita-Salute San Raffaele University, Milan, Italy  IRCCS San Raffaele Scientific Institute, Milan, Italy  Sapienza University of Rome and IRCCS Neuromed Pozzilli, Rome, Italy  Sapienza University of Rome, Rome, Italy  University of Campania Luigi Vanvitelli, Naples, Italy  University of Siena, Siena, Italy