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Aerobic Training and Potential Neurogenesis in Progressive Multiple Sclerosis: Focus on the Hippocampus and the Subventricular Zone

Author:Morozumi, Tetsu   Valsasina, Paola   Preziosa, Paolo   Meani, Alessandro   Motl, Rob   Amato, Maria   Brichetto, Giampaolo   Boccia, Vincenzo Daniele   Chataway, Jeremy   Chiaravalloti, Nancy   Cutter, Gary   Dalgas, Ulrik   DeLuca, John   Farrell, Rachel   Feys, Peter   Freeman, Jennifer   Inglese, Matilde   Meza, Cecilia   Salter, Amber   Sandroff, Brian   Feinstein, Anthony   Filippi, Massimo   Rocca, Maria   

Session Name:S8: Multiple Sclerosis: Imaging, Biomarkers, and Environmental Exposures  

Topic:Multiple Sclerosis  

Program Number:S8.006  

Author Institution:IRCCS San Raffaele Scientific Institute  and Vita-Salute San Raffaele University, Milan, Italy  IRCCS San Raffaele Scientific Institute, Milan, Italy  University of Illinois Chicago, Chicago, IL  University of Florence  and IRCCS Fondazione Don Carlo Gnocchi, Firenze, Italy  Italian MS Society, Genoa, Italy  University of Genoa, Genoa, Italy  University College London, and University College London Hospitals, London, United Kingdom  Kessler Foundation , West Orange, NJ  University of Alabama At Birmingham, Birmingham, AL  Aarhus University, Aarhus, Denmark  University College London, London, United Kingdom  Hasselt University and UMSC Hasselt, Diepenbeek, Belgium  University of Plymouth, Plymouth, United Kingdom  University of Genoa and IRCCS Ospedale Policlinico San Martino, Genoa, Italy  University of Toronto and Sunnybrook Health Sciences Centre, Toronto, ON, Canada  UT Southwestern Medical Center, Dallas, TX  

ORATORIO-HAND: Results of the Primary Analysis of Ocrelizumab vs Placebo in Primary Progressive Multiple Sclerosis, Including Older Patients and Those With More Advanced Disease

Author:Giovannoni, Gavin   Airas, Laura   Bove, Riley   Cutter, Gary   Hobart, Jeremy   Kuhle, Jens   Montalban, Xavier   Tur, Carmen   Wolinsky, Jerry   Schneble, Hans-Martin   Baldinotti, Anna   Bonati, Ulrike   Giacobino, Caroline   Wang, Qing   Yang, Ke   Oh, Jiwon   

Session Name:S40: Multiple Sclerosis: Clinical Trials/Science and Real-world Evidence  

Topic:Multiple Sclerosis  

Program Number:S40.001  

Author Institution:Department of Neurology, Royal London Hospital, Barts Health NHS Trust, London, UK and Blizard Institute, Queen Mary University, London, UK, London, United Kingdom  University of Turku, Turku, Finland, Turku, Finland  UCSF Weill Institute for Neuroscience, Department of Neurology, University of California San Francisco, San Francisco, CA, USA, CA  The University of Alabama at Birmingham, School of Public Health, Birmingham, AL, USA, Birmingham, AL  Peninsula Medical School, Plymouth University, UK, Plymouth, United Kingdom  MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland, Switzerland  Centre d'Esclerosi Múltiple de Catalunya, Vall d'Hebron University Hospital, Barcelona, Spain, Barcelona, Spain  Queen Square MS Centre, Department of Neuroinflammation, Institute of Neurology, Faculty of Brain Sciences, University College London (UCL), London, UK/Neurology-Neuroimmunology Department, Multiple Sclerosis Centre of Catalonia (CEMCAT), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain, Un  Department of Neurology, University of Texas Health Science Center, Houston, TX, USA, TX  F. Hoffmann-La Roche Ltd, Basel, Switzerland, Switzerland  F. Hoffmann-La Roche Ltd, Basel, Switzerland, Basel, Switzerland  Division of Neurology, Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada, ON, Canada  

MG-ADL Subdomain Score Changes With Eculizumab or Ravulizumab: An Analysis of the Global MG SPOTLIGHT Registry

Author:Juel, Vern   Macwan, Samir   Sacca, Francesco   Gordon, Andrew   Zeinali, Lida   Winkley, James   Liu, Chuang   Cutter, Gary   Dodig, Dubravka   Alpers, Joshua   Tandan, Rup   

Session Name:P4: Neuromuscular and Clinical Neurophysiology (EMG): Neuromuscular Junction Disorders  

Topic:Neuromuscular and Clinical Neurophysiology (EMG)  

Program Number:P4.008  

Author Institution:Duke University, Durham, NC  Eisenhower Health Center, Rancho Mirage, CA  University of Naples Federico II, Napoli, Italy  Northwest Neurology, Ltd., Lake Barrington, IL  Alexion, AstraZeneca Rare Disease, Mississauga, ON, Canada  Baptist Health Medical Group Neurology, Lexington, KY  Alexion, AstraZeneca Rare Disease, Baar, Switzerland  University of Alabama At Birmingham, Birmingham, AL  University of Toronto/Toronto Western Hospital, Toronto, ON, Canada  Erlanger Medical Center, Chattanooga, TN  University of Vermont Medical Center, Burlington, VT  

Efficacy and Safety of Frexalimab in Participants With Relapsing Multiple Sclerosis: 3-Year Results From the Phase 2 Open-label Extension

Author:Vermersch, Patrick   Krieger, Stephen   Wiendl, Heinz   Granziera, Cristina   Mao-Draayer, Yang   Cutter, Gary   Kalbus, Oleksandr   Staikov, Ivan   Dufek, Michal   Montalban, Xavier   Saubadu, Stephane   Luo, Xiaodong   Smyth, Brendan   Djukic, Biljana   Truffinet, Philippe   Wallstroem, Erik   Giovannoni, Gavin   

Session Name:P7: Multiple Sclerosis: Clinical Trials 1  

Topic:Multiple Sclerosis  

Program Number:P7.003  

Author Institution:University of Lille, Inserm U1172 LilNCog, CHU Lille, FHU Precise, Lille, France, Lille, France  Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Icahn School of Medicine at Mount Sinai, New York, NY, United States, New York, NY  Department of Neurology and Neurophysiology, University of Freiburg, Freiburg, Germany  Brain & Mind Institute, University of Sydney, Sydney, Australia, Freiburg im Breisgau, Germany  Translational Imaging in Neurology (ThINk) Basel, Department of Biomedical Engineering, Faculty of Medicine  Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland, Basel, Switzerland  Autoimmunity Center of Excellence, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States, Oklahoma City, OK  Department of Biostatistics, UAB School of Public Health, Birmingham, AL, United States, Birmingham, AL  Department of Neurology, Dnipro State Medical University, Dnipro, Ukraine, Dnipro, Ukraine  Clinic of Neurology and Sleep Medicine, Acibadem City Clinic University Hospital Tokuda, Sofia, Bulgaria, Sofia, Bulgaria  First Department of Neurology, St. Anne’s University Hospital, Faculty of Medicine, Masaryk University, Brno, Czech Republic, Brno, Czech Republic  Multiple Sclerosis Centre of Catalonia, Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Spain , Barcelona, Spain  Sanofi, Gentilly, France, Chilly Mazarin, France  Sanofi, Morristown, NJ, United States, Morristown, NJ  Sanofi, Cambridge, MA, United States, Cambridge, MA  Queen Mary University of London, London, United Kingdom, London, United Kingdom  

Concomitant Immunosuppressive Therapy Use With Ravulizumab: Analysis of the Global MG SPOTLIGHT Registry

Author:Nowak, Richard   Habib, Ali   Meisel, Andreas   Scheiner, Christopher   Zeinali, Lida   Liu, Chuang   Pulley, Michael   Cutter, Gary   Gordon, Andrew   

Session Name:P9: Neuromuscular and Clinical Neurophysiology (EMG): Myasthenia Gravis Clinical Trials  

Topic:Neuromuscular and Clinical Neurophysiology (EMG)  

Program Number:P9.016  

Author Institution:Yale University School of Medicine, New Haven, CT  University of California, Irvine, Irvine, CA  Charité Universitätsmedizin Berlin, Berlin, Germany  University of Tennessee Medical Center, Knoxville, TN  Alexion, AstraZeneca Rare Disease, Mississauga, ON, Canada  Alexion, AstraZeneca Rare Disease, Baar, Switzerland  University of Florida Jacksonville, Jacksonville, FL  University of Alabama At Birmingham, Birmingham, AL  Northwest Neurology, Ltd., Lake Barrington, IL