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Fenfluramine in CDKL5 Deficiency Disorder: Primary Efficacy and Safety Results from a Phase 3, Randomized, Double-blind, Placebo-controlled Study

Author:Moseley, Brian   Specchio, Nicola   Marsh, Eric   Devinsky, Orrin   Aledo-Serrano, Ángel   Immacolata Battaglia, Domenica   Rajaraman, Rajsekar   Keough, Karen   Honda, Ryoko   Guerrini, Renzo   Melikishivili, Gia   Amin, Sam   Jaksha, Amanda   St. Wecker, Peter   Kilgallen, Brian   Dickson, Najla   Sullivan, Joseph   

Session Name:S5: Clinical Epilepsy  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:S5.010  

Author Institution:UCB, Morrisville, NC  Bambino Gesù Children’s Hospital, IRCCS, Member of European Reference Network (ERN) EpiCARE  University Hospitals KU, Rome, Italy  Children's Hospital of Philadlephia  Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA  NYU Epilepsy Center, New York, NY  Neuroscience Institute, Vithas Madrid La Milagrosa University Hospital, Madrid, Spain  Fondazione Policlinico Universitario Agostino Gemelli, IRCCS  Università Cattolica del Sacro Cuore, Rome, Italy  David Geffen School of Medicine  UCLA Mattel Children’s Hospital, Los Angeles, CA  Child Neurology and Consultants of Austin, Austin, TX  Nagasaki Medical Center, Omura, Nagasaki, Japan  Meyer Children's Hospital IRCCS, Member of the ERN EpiCARE  University of Florence, Florence, Italy  MediClubGeorgia Medical Center, Tbilisi, Georgia  University Hospitals Bristol and Weston, Bristol, United Kingdom  Patient caregiver, Denver, CO  UCB, Emeryville, CA  Weill Institute for Neurosciences and Benioff Children’s Hospital, University of California San Francisco, San Francisco, CA  

Vormatrigine Rapidly Reduces Seizures in Adults with Treatment-resistant Epilepsy: Results from the RADIANT Study

Author:Hansen, Karl   Mohsen, Bashar   Epstein, Noam   Hernandez, Maribel   Sniecinski, Megan   Crimin, Kimberly   Tang, Minao   Petrou, Steven   Souza, Marcio   Devinsky, Orrin   Aledo-Serrano, Angel   

Session Name:P11: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P11.003  

Author Institution:Praxis Precision Medicines, Boston, MA  Assertive Research Center, FL  Praxis Precision Medicines, MA  NYU Langone Comprehensive Epilepsy Center, New York, NY  Epilepsy Unit, Clinical Neuroscience Department, Blua Sanitas Valdebebas Hospital, Spain