Objective Life-space Mobility in Latino Aging: Cognitive, Cardiovascular, and Sociocultural Correlates in the SALUD-tech Study
Andrea Mendez Colmenares1, Emma Churchill2, Tess Filip3, Lizbeth Murillo1, Linda Gallo4, Alexander Demos5, Erin Sundermann6, Douglas Galasko6, Luis Betancourt6, Kassandra Portillo6, Rebecca Daly6, Raeanne Moore6, Maria Marquine1
1Duke University, 2University of Central Florida, 3University of Iowa, 4San Diego State University, 5University of Illinois at Chicago, 6University of California, San Diego
Objective:
This study examined life-space mobility and its correlates among Latino persons at varying risk for Alzheimer’s disease and related dementias (ADRD).
Background:
Life-space mobility is the degree to which people move through their environments and has been most commonly assessed via self-report. Reduced life space mobility has been linked to increased risk for ADRD. Research on objective life-space mobility is limited, particularly among Latino older adults, who experience a higher ADRD burden.
Design/Methods:
Participants included 176 Latino adults residing in California (age 50-70, 74% female) who completed comprehensive neuropsychological and medical evaluations. We classified participants into ADRD risk groups based on the presence or absence of mild cognitive impairment (MCI) and cardiovascular (CVD) risk. Life-space mobility was measured using smartphone GPS data collected over 7-30 days and quantified by the daily average distance traveled (total kilometers and furthest distance from home). Demographic and sociocultural variables included age, sex,
years of education, paternal/maternal education, household income/household size, country of birth, years lived in the U.S., and cross-border travel.
Conclusions:
CVD risk was strongly associated with reduced life-space mobility in this Latino cohort, indicating that GPS technology might help identify patterns of behavior that reflect biological vulnerability. Patterns of life space mobility differed among subgroups of Latinos, underscoring the need to consider Latino heterogeneity. Life space mobility, as assessed by GPS, might be an important digital biomarker of risk for developing dementia with a vascular contribution. Future longitudinal studies examining incidence of dementia will help best determine causality.
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