To review utilization of an asynchronous case-based neurology curriculum over a 2-year period. 

Many health professions training programs lack a required or standardized neurology clinical experience. The American Academy of Neurology published a recommended neurology curriculum guideline in 2019. Our group designed a case-based neurology curriculum mapped to these guidelines, with emphasis on clinical reasoning, based on the Aquifer™ online platform.

The neurology curriculum was initially published on the Aquifer platform in July 2023. All cases have specific learning objectives, follow a standardized template, and are interactive with embedded questions and explanations. Cases were written by neurologists and underwent peer and editor review prior to publishing. The cases are subjected to yearly iterative review after publication, to ensure up to date content and incorporate feedback from learners. A self-assessment test, Calibrate™, was added in July of 2025. AI-generated feedback on case summary statements was recently incorporated.  

As of October 2025, there are 15 published cases, with 18 scheduled to be published by July 2026. 198 health professions programs have access to Aquifer Neurology cases, including 104 MD, 15 DO, 61 PA, and 18 NP programs. Of the case utilizers, 68% (n= 6676) are MD students, 17% (n = 1631) are PA students, 5% (n=502) NP students, 10% (n=935) DO students. The two most highly utilized cases are 1) Evaluation and workup for an unconscious patient and 2) History and evaluation for polyneuropathy. The median (IQR) annual rating for all cases was 4.6 (4.4-4.7) on a 5-point Likert scale.

A comprehensive, peer-reviewed, case-based online neurology curriculum was successfully created and published with robust utilization by a diverse group of health professions students. Future directions include adding interactive patient encounters with an AI-generated tool to provide specific and actionable feedback to students on their interviewing style and illness scripts.