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Safety and Effectiveness of Fenfluramine for the Treatment of Seizures in Lennox-Gastaut Syndrome: Results From the Final Analysis of an Open-Label Extension Study

Author:Knupp, Kelly   Scheffer, Ingrid   Ceulemans, Berten   Sullivan, Joseph   Nickels, Katherine   Lagae, Lieven   Guerrini, Renzo   Zuberi, Sameer   Nabbout, Rima   Riney, Kate   Lock, Michael   Dai, David   Davis, Ronald   Morita, Diego   Lothe, Amélie   Langlois, Mélanie   Zhang-Roper, Re   

Session Name:P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P8.002  

Author Institution:Children's Hospital Colorado, Aurora, CO  University of Melbourne, Austin Hospital and Royal Children's Hospital, Florey and Murdoch Children’s Research Institutes, Melbourne, Australia  Antwerp University Hospital, Antwerp, Belgium  University of California San Francisco Weill Institute for Neurosciences, Benioff Children’s Hospital, San Francisco, CA  Mayo Clinic, Rochester, MN  Member of the European Reference Network EpiCARE, University of Leuven, Leuven, Belgium  Meyer Children’s Hospital IRCCS, and University of Florence, Florence, Italy  Paediatric Neurosciences Research Group, Royal Hospital for Children, Glasgow, United Kingdom  Member of European Reference Network EpiCARE, Reference Centre for Rare Epilepsies, Necker Enfants Malades Hospital, APHP, U 1163 Institut Imagine, Université Paris Cité, Paris, France  The University of Queensland, St Lucia  Queensland Children's Hospital, South Brisbane, Australia  Independent Statistical Consultant, Haiku, HI  Syneos Health, Morrisville, NC  Neurology and Epilepsy Research Center, Orlando, FL  UCB, Brussels, Belgium  Hospital Ruber Internacional, Madrid, Spain  

A Stratified Analysis of Efficacy and Safety of Fenfluramine in Patients With Dravet Syndrome

Author:Nabbout, Rima   Sullivan, Joseph   Auvin, Stéphane   Ceulemans, Berten   Cross, J Helen   Devinsky, Orrin   Gil-Nagel, Antonio   Guerrini, Renzo   Knupp, Kelly   Perry, M Scott   Sanchez-Carpintero, Rocio   Scheffer, Ingrid   Specchio, Nicola   Strzelczyk, Adam   Wheless, James   Wirr,   

Session Name:P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P8.014  

Author Institution:Member of European Reference Network EpiCARE, Reference Centre for Rare Epilepsies, Necker Enfants Malades Hospital, APHP, U 1163 Institut Imagine, Université Paris Cité, Paris, France  University of California San Francisco Weill Institute for Neurosciences, Benioff Children’s Hospital, San Francisco, CA  Service de Neurologie Pédiatrique & INSERM U1141, Robert Debré University Hospital, APHP, Paris, France  University of Antwerp, Antwerp University Hospital, Antwerp, Belgium  UCL NIHR BRC Great Ormond Street Institute of Child Health, Great Ormond Street Hospital, London, United Kingdom  Comprehensive Epilepsy Center, NYU Langone Medical Center, New York, NY  Hospital Ruber Internacional, Madrid, Spain  Meyer Children’s Hospital IRCCS, University of Florence, Florence, Italy  Children's Hospital Colorado, Anschutz Medical Campus, Aurora, CO  Cook Children’s Medical Center, Fort Worth, TX  Clinica Universidad de Navarra, Pediatric Neurology Unit, Pamplona, Spain  University of Melbourne, Austin Hospital and Royal Children’s Hospital, Florey and Murdoch Children’s Research Institutes, Melbourne, Australia  Member of European Reference Network EpiCARE, Bambino Gesú Children’s Hospital, IRCCS , Rome, Italy  Goethe University Frankfurt, Epilepsy Center Frankfurt Rhine-Main & University Hospital Frankfurt, Frankfurt am Main, Germany  University of Tennessee Health Science Center & Le Bonheur Children’s Hospital, Memphis, TN  Mayo Clinic/Dept of Child Neurology, Rochester, MN  UCB, Brussels, Belgium  Member of the European Reference Network EpiCARE, University of Leuven, Leuven, Belgium  

Real-World Use of Fenfluramine for Dravet Syndrome: a Retrospective Cohort Study Using a National Pharmacy Database

Author:Lhatoo, Samden   Kerr, Wesley   Wirrell, Elaine   Donner, Elizabeth   Sullivan, Joseph   Guerrini, Renzo   Scheffer, Ingrid   Rheims, Sylvain   Cross, J Helen   Lagae, Lieven   Ryvlin, Philippe   Gil-Nagel, Antonio   Noebels, Jeffrey   Roberts, Jenna   Lothe, Amélie   Tryfon, Milena   R,   

Session Name:P12: Epilepsy/Clinical Neurophysiology (EEG): Retrospective Studies, Reviews, and Meta-analyses in Epilepsy  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P12.002  

Author Institution:University of Texas Houston Health Sciences Center, Houston, TX  University of Pittsburgh, Pittsburgh, PA  Mayo Clinic/Dept of Child Neurology, Rochester, MN  The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada  University of California San Francisco Weill Institute for Neurosciences, Benioff Children’s Hospital, San Francisco, CA  Anna Meyer Children's Hospital, University of Florence, Florence, Italy  University of Melbourne, Austin Hospital and Royal Children's Hospital, Florey and Murdoch Children’s Research Institutes, Melbourne, Australia  Hospices Civils de Lyon and Lyon 1 University, Lyon, France  UCL NIHR BRC Great Ormond Street Institute of Child Health, Great Ormond Street Hospital, London, United Kingdom  Member of the European Reference Network EpiCARE, University of Leuven, Leuven, Belgium  University of Lausanne, Lausanne, Switzerland  Hospital Ruber Internacional, Madrid, Spain  Baylor College of Medicine, Houston, TX  UCB, Brussels, Belgium  NYU Langone Medical Center, New York, NY