Risk Factors for Neurological Outcomes in Patients with Posterior Stroke in Latin America Patients: A Systematic Review
Fritz Fidel Váscones-Román1, Carlos Rodrigo Vicuña2, Martha Vilca Salas1, Karlos Acurio3, Brigith Avila Lucas1, Luis Aguilar Alvarez4, Wagner Rios-Garcia5, Niels Pacheco6
1Cayetano Heredia Peruvian University, 2universidad nacional mayor de san marcos, 3Universidad Peruana Cayetano Heredia, 4Universidad Nacional de Cajamarca, 5Universidad Nacional San Luis Gonzaga, 6Harvard Medical School
Objective:
To summarize the current evidence about risk factors for the neurological outcomes for posterior stroke in Latin America patients
Background:
Ischemic stroke of the posterior cerebral circulation accounts for up to 25% of all cases and poses challenges because of its variable presentation, especially in the Latino population where there is a lack of evidence.
Design/Methods:
We systematically searched 4 databases up to July 2024 for studies evaluating patients with subsequent stroke in Latin America. The risk of bias was assessed with the Newcastle Ottawa scale and ROBINS-I.
Results:
Three cohort studies (1284 patients) conducted in Chile, Brazil and Mexico were selected. One of the studies found that at 6 months, most patients had a good prognosis (mRS score 0-2) (45%; 95% CI: 34-5-56-0). Another study found that for the development of Homonymous Visual Field Defects, vertebral artery dissection (OR: 12.65; 95% CI: 1.01-157.2) and hypercoagulable states (OR: 12.30; 95% CI: 1.02-147.9) were risk factors. Another study found that in patients treated with thrombectomy, the main factors for mortality, good prognosis and intracranial hemorrhage were a baseline NIHSS > 10 (OR: 62.78; 95% CI: 1.67-2358.8), proximal basilar occlusion V4 (OR: 10.26; 95% CI: 1.45-72.15) and an expanded treatment in cerebral infarction (eTICI) of 0-2a (OR: 8.29; 95% CI: 1.06-64.45), respectively.
Conclusions:
Despite the scarce evidence, neurological outcomes in patients with posterior stroke are related to factors such as elevated NIHSS, basilar occlusion, eTICI, among others; however, future studies are needed to evaluate the Latin American population.
Disclaimer: Abstracts were not reviewed by Neurology® and do not reflect the views of Neurology® editors or staff.