2025 American Academy of Neurology Abstract Website

Mariana Medina-Soler¹, David Lizarazo², Johan Trigos³, Juan Martinez-Lemus⁴, Oscar Briceño³, Hugo Paez³, Maria I Reyes-Mantilla¹
¹Departamento de Neurología, Subred Integrada de Salud Norte, Bogotá, ²Semillero de Neuroepidemiología, Subred Integrada de Salud Norte, Bogotá, ³Departamento de Infectología, Subred Integrada de Salud Norte, Bogotá, ⁴UTHealth Houston, McGovern Medical School, Houston, TX, United States of America

Objective:

Describe variables associated with outcomes in patients who were followed up in a continuity clinic for ND disorders in a tertiary center in Bogota, Colombia, from 2022 to 2024.

Background:

A continuity clinic for neuroinfectious disorders (ND) was established in 2022. A high prevalence of unfavorable intrahospital outcomes is seen in 42% of our patients. Data regarding access, treatment adherence, and functional outcomes must be monitored in the outpatient setting.

Design/Methods:

The modified Rankin scale (mRs) was calculated at discharge and reassessed by a telephone-based interview within the next twelve months. Poor outcomes were defined as mRs 3-5. Differences between subgroups were evaluated with χ2. A logistic regression was developed to determine correlations with poor functional outcomes.

Results:

One hundred and sixty-four patients with ND were evaluated by the time of discharge at our center during that period. More than half of them (n=86, 52%) were successfully contacted for a follow-up visit. The remaining were either deceased (n=17, 10%) or lost on follow-up (n=61, 38%). Most of the patients (n=118, 72%) were HIV-positive. An in-person evaluation was completed in 53.2% (n=41) of the cases. Most visits occurred 12 months post-discharge (n=31, 55.4%). Poor functional outcomes were documented in 22% (n=36) of the cases. Residual neurological symptoms were noted in half of the patients (n=38, 50.7%), 90.3% (n=65) were self-reported compliant with treatment, 32% (n=23) had access to a neurorehabilitation plan, and most of the patients reported the presence of family support (n=66, 40%). Patients with poor functional outcomes were older with a median age of 40 years old (IQR 33-56, p=0.02) and HIV positive (OR 3.32,p=0.039).

Conclusions:

More than half of the patients were scheduled for a follow-up visit at our ND continuity clinic. Older age and VIH were associated with poor outcomes in the outpatient setting.