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Binding Characteristics of PRX012 Surrogate Demonstrate Potent Engagement of Toxic Amyloid Beta Protofibrils and Robust Clearance of Pyroglutamate-modified Amyloid Beta

Binocular Visual Function Testing in an Alzheimer’s Disease Research Center (ADRC) Cohort: Low-contrast Letter Acuity and Rapid Automatized Naming (RAN) Tasks of MULES and SUN

Biofluid Activity and Levels of the Angiotensin-converting Enzyme Are Surrogates for Diverse Cerebrospinal Fluid Amyloid-beta Effects in Dementia with Lewy Bodies and Alzheimer’s Dementia

Biological Staging of the Parkinson’s Progression Markers Initiative (PPMI) Cohort Using the Research Neuronal a-synuclein Disease Integrated Staging System (NSD-ISS)

Author:Tanner, Caroline   Simuni, Tanya   Chahine, Lana   Poston, Kathleen   Brumm, Michael   Chowdry, Sohini   Coffey, Christopher   Concha-Marambio, Luis   Dam, Tien   DiBiaso, Peter   Foroud, Tatiana   Frasier, Mark   Gochanour, Caroline   Jennings, Danna   Kieburtz, Karl   Kopil, Catherine   Merchant, Kalpana   Mollenhauer, Brit   Montine, Thomas   Nudelman, Kelly   Pagano, Gennaro   Seibyl, John   Sherer, Todd   Singleton, Andrew   Stephenson, Diane   Stern, Matthew   Soto, Claudio   Tolosa, Eduardo   Weintraub, Daniel   Xiao, Yuge   Siderowf, Andrew   Poewe, Werner   Marek, Kenneth   

Session Name:P11: Movement Disorders: Parkinson's Disease Epidemiology, Genetics, and Biomarkers 2  

Topic:Movement Disorders  

Program Number:P11.009  

Author Institution:University of California San Francisco, Weill Institute for Neurosciences, San Francisco, CA  Northwestern University Feinberg School of Medicien, Chicago, IL  University of Pittsburgh, Pittsburgh, PA  Stanford University, Stanford, CA  University of Iowa, Iowa City, IA  The Michael J. Fox Foundation for Parkinson's Research, New York, NY  Amprion, San Francisco, CA  Neumora Therapeutics Inc, Watertown, MA  Indiana University School of Medicine, Indianapolis, IN  Denali Therapeutics, South San Francisco, CA  University of Rochester Medical Center, Rochester, NY  Northwestern University, Chicago, IL  University of Goettingen, Goettingen, Germany  Indiana University , Indianapolis, IN  F. Hoffmann-La Roche Ltd, Basel, Switzerland  Institute for Neurodegenerative Disorders, Branford, CT  National Institute of Aging, Bethesda, MD  Critical Path Institute, Tucson, AZ  University of Pennsylvania, Philadelphia, PA  University of Texas McGovern Medical School , Houston, TX  Unviersity of Barcelona, Barcelona, Spain  University of Pennsylvania, Narberth, PA  University Hospital of Neurology, Innsbruck, Austria  Institute for Neurodegenerative Disorders, New Haven, CT