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B-Cell Depletion and Efficacy Outcomes of Ofatumumab Are Consistent Across Different Body Mass Index Categories: Insights from ASCLEPIOS I and II Trials

Author:Cross, Anne   Hauser, Stephen   Wiendl, Heinz   Bar-Or, Amit   Coyle, Patricia   Montalban, Xavier   De Seze, Jerome   Fu, Haoyi   Bhatt, Alit   Boer, Ibolya   Kappos, Ludwig   

Session Name:P9: Multiple Sclerosis: Clinical Trials and Therapeutics (including Safety) 2  

Topic:Multiple Sclerosis  

Program Number:P9.002  

Author Institution:Washington University School of Medicine, Saint Louis, MO, USA, Clayton, MO  UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, USA, San Francisco, CA  University of Münster, Münster, Germany, Muenster, Germany  Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, PA, USA, Philadelphia, PA  Department of Neurology, Stony Brook University, Stony Brook, NY, USA, Stony Brook, NY  Department of Neurology-Neuroimmunology, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitario Vall d'Hebron, Barcelona, Spain, Barcelona, Spain  University Hospital of Strasbourg, Strasbourg, France, Strasbourg, France  Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA, East Hanover, NJ  Novartis Healthcare Pvt. Ltd., Hyderabad, India, Hyderabad, India  Novartis Pharma AG, Basel, Switzerland, Basel, Switzerland  Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB) and MS Center, Departments of Headorgans, Spine and Neuromedicine, Clinical Research, Biomedicine and Biomedical Engineering, University Hospital and University of Basel, Basel, Switzerland, Basel, Switzerland  

Humoral Signatures of MOG-antibody Associated Disease Track with Age and Disease Activity

Author:Spatola, Marianna   Chuquisana, Omar   Jung, Wonyeong   Lopez, Joseph   Wendel, Eva Maria   Ramanathan, Sudarshini   Keller, Christian   Hahn, Tim   Meinl, Edgar   Reindl, Markus   Dale, Russell   Wiendl, Heinz   Lauffenburger, Douglas   Rostasy, Kevin   Brilot, Fabienne   Alter, Galit   Lunemann, Jan   

Session Name:P9: Autoimmune Neurology: MOGAD  

Topic:Autoimmune Neurology  

Program Number:P9.006  

Author Institution:Ragon Institute of MGH, MIT and Harvard Medical School, Cambridge, MA  Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Munster, Germany  Brain Autoimmunity Group, Kids Neuroscience Centre, Kids Research at the Children's Hospital at Westmead, Westmead, Australia  Department of Pediatric Neurology, Olgahospital/Klinikum Stuttgart, Stuttgart, Germany  Department of Neurology, Concord Hospital, Sidney, Australia  Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany  Institute for Translational Psychiatry, University of Münster, Münster, Germany  Institute of Clinical Neuroimmunology, Biomedical Center and University Hospital, Ludwig-Maximilians-Universität , Munich, Germany  Clinical Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria  Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Muenster, Germany  Massachusetts Institute of Technology, Cambridge, MA  Department of Pediatric Neurology, Children's Hospital Datteln, University Witten/Herdecke, Datteln, Germany  Brain and Mind Centre, The University of Sydney, Westmead, Australia  

Long-term Effect of Ofatumumab on Serum Immunoglobulin Levels in Patients with Relapsing Multiple Sclerosis

Author:Bar-Or, Amit   Wiendl, Heinz   De Seze, Jerome   Correale, Jorge   Cross, Anne   Derfuss, Tobias   Selmaj, Krzysztof   Winthrop, Kevin   Giacomini, Paul   Sacca, Francesco   Hu, Xixi   Sullivan, Roseanne   Jehl, Valentine   Boer, Ibolya   Bhatt, Alit   Hauser, Stephen   

Session Name:P9: Multiple Sclerosis: Clinical Trials and Therapeutics (including Safety) 2  

Topic:Multiple Sclerosis  

Program Number:P9.007  

Author Institution:Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA  University of Muenster, Muenster, Germany  University Hospital of Strasbourg, Strasbourg, France  Institute for Neurological Research Dr. Raul Carrea, Buenos Aires, Argentina  Washington University School of Medicine, Clayton, MO  Neurology Clinic and Policlinic and Research Center for Clinical Neuroimmunology and Neuroscience, Departments of Medicine and Biomedicine, University Hospital and University of Basel, Basel, Switzerland  Center for Neurology, Lodz, Lodz, Poland  Public Health and Preventive Medicine, Division of Infectious Diseases, Oregon Health and Sciences University, Portland, OR  Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, Canada  NSRO Department, University “Federico II” of Naples, Naples, Italy  Novartis Pharmaceuticals Corporation, East Hanover, NJ  Novartis Pharma AG, Basel, Switzerland  Novartis Healthcare Pvt. Ltd., Hyderabad, India  UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA  

Longer-term Safety and Efficacy of Ofatumumab in People with Relapsing Multiple Sclerosis for Up to 6 Years

Author:Wiendl, Heinz   Hauser, Stephen   Nicholas, Jacqueline   De Seze, Jerome   Meuth, Sven   Giacomini, Paul   Robertson, Derrick   Wray, Sibyl   Bhatt, Alit   Hu, Xixi   Fu, Haoyi   Jehl, Valentine   Sullivan, Roseanne   Boer, Ibolya   Cohen, Jeffrey   Kappos, Ludwig   

Session Name:P9: Multiple Sclerosis: Clinical Trials and Therapeutics (including Safety) 2  

Topic:Multiple Sclerosis  

Program Number:P9.010  

Author Institution:University of Münster, Münster, Germany, Muenster, Germany  UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA, United States, San Francisco, CA  OhioHealth Multiple Sclerosis Center, Columbus, OH, USA, Columbus, OH  University Hospital of Strasbourg, Strasbourg, France, Strasbourg, France  Department of Neurology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany, Duesseldorf, Germany  Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada, Montreal, QC, Canada  Multiple Sclerosis Division, Department of Neurology, University of South Florida, Tampa, FL, USA, Tampa, FL  Hope Neurology MS Center, Knoxville, TN, USA, Knoxville, TN  Novartis Healthcare Pvt. Ltd., Hyderabad, India, Hyderabad, India  Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA, Morristown, NJ  Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA, East Hanover, NJ  Novartis Pharma A.G. Basel, Switzerland, Basel, Switzerland  Department of Neurology, Mellen MS Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA, Cleveland, OH  Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB) and MS Center, Departments of Headorgans, Spine and Neuromedicine, Clinical Research, Biomedicine and Biomedical Engineering, University Hospital and University of Basel, Basel, Switzerland, Basel, Switzerland  

Long-term Safety, Tolerability, and Efficacy of Subcutaneous Efgartigimod PH20 in Participants with Generalized Myasthenia Gravis: Interim Results of the ADAPT-SC+ Study

Author:Howard, James   Li, Yuebing   Vu, Tuan   Korobko, Denis   Steeland, Sophie   Van Hoorick, Benjamin   Podhorna, Jana   Hodari, Moana   Utsugisawa, Kimiaki   Sacca, Francesco   Wiendl, Heinz   De Bleecker, Jan   Mantegazza, Renato   

Session Name:P10: Neuromuscular and Clinical Neurophysiology (EMG): Myasthenia Gravis 3  

Topic:Neuromuscular and Clinical Neurophysiology (EMG)  

Program Number:P10.008  

Author Institution:Department of Neurology, The University of North Carolina, Chapel Hill, North Carolina, Chapel Hill, NC  Cleveland Clinic, Cleveland, Ohio, Cleveland, OH  Department of Neurology, University of South Florida Morsani College of Medicine, Tampa, Florida, Tampa, FL  State Budgetary Healthcare Institution of Novosibirsk Region "State Novosibirsk Regional Clinical Hospital," Novosibirsk, Russia, Novosibirsk, Russian Federation  argenx, Ghent, Belgium, Ghent, Belgium  argenx, Ghent, Belgium, Ghent , Belgium  argenx, Ghent, Belgium, Wiesbaden, Germany  argenx, Ghent, Belgium, Camberley, United Kingdom  Department of Neurology, Hanamaki General Hospital, Hanamaki, Japan, Hanamaki, Japan  NRSO Department, Federico II University of Naples, Naples, Italy, Napoli, Italy  Department of Neurology, University of Münster, Münster, Germany, Muenster, Germany  Ghent University Hospital, Ghent, Belgium , Gent, Belgium  Department of Neuroimmunology and Neuromuscular Diseases, Fondazione Istituto Neurologico Carlo Besta, Milan, Italy, Milan, Italy