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              Development of eIF2B Activator ABBV-CLS-7262 as a Novel Treatment for Vanishing White Matter Disease

              Author:Baruch, Amos   Malik, Paul   Gopathi, Anu   Ingalla, Ellen   Rosebraugh, Matthew   Han, Yi Rang   Bellemin, Emmanuelle   Serone, Adrian   Fausch, Steven   Asundi, Jyoti   Kolumam, Ganesh   Zhang, Chunlian   Zavala-Solorio, Jose   Donnelly-Roberts, Diana   Challagundla, Malleswari   Boch, Christina   Cao, Charlie   Mohler, Eric   Sidrauski, Carmela   Bonkowsky, Joshua   Jeong, Anna   Cho, William   

              Session Name:P2: Child Neurology and Developmental Neurology: Pediatric White Matter  

              Topic:Child Neurology and Developmental Neurology  

              Program Number:P2.001  

              Author Institution:Calico Life Sciences, South San Francisco, CA  AbbVie, North Chicago, IL  AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany  Abbvie, North Chicago, CA  University of Utah, Salt Lake City, UT  

              Phase 1 Asian PK Study of ABBV-CLS-7262, an eIF2B Activator Being Developed as a Potential Treatment for Amyotrophic Lateral Sclerosis and Vanishing White Matter Disease

              Author:Han, Yi Rang   Malik, Paul   Huang, Xiu   Boiser, Joey   Jeong, Anna   Siovitz, Lucia   Stodtmann, Sven   Cho, Bill   Rosebraugh, Matthew   

              Session Name:P5: Neuromuscular and Clinical Neurophysiology (EMG): Amyotrophic Lateral Sclerosis 1  

              Topic:Neuromuscular and Clinical Neurophysiology (EMG)  

              Program Number:P5.014  

              Author Institution:AbbVie, North Chicago, IL  Calico Life Sciences, South San Francisco, CA  AbbVie, Chicago, IL  AbbVie, Ludwigshafen Am Rhein, Germany  Calico, South San Francisco, CA