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Inverting the Drug Discovery Funnel: In Vivo First Screening for mAb Blood-brain Barrier Penetration Yields Molecules with Novel Uptake Properties

Author:Ogden, Pierce   Garcia, Alvaro   Alioto, Salvatore   Nichols, Mike   Nudel, Kate   Carroll, Sean   Avera, John   Gerew, Alex   Anand, Anisha   Ho-Rath, Yendee   Lofgren, Shane   Reis, Alex   Malekoltojari, Ainaz   Stoica, Anca Ioana   

Session Name:P8: General Neurology: Assorted Neurologic Basic Science  

Topic:General Neurology  

Program Number:P8.007  

Author Institution:Manifold Bio, Boston, MA