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Development of eIF2B Activator ABBV-CLS-7262 as a Novel Treatment for Vanishing White Matter Disease

Author:Baruch, Amos   Malik, Paul   Gopathi, Anu   Ingalla, Ellen   Rosebraugh, Matthew   Han, Yi Rang   Bellemin, Emmanuelle   Serone, Adrian   Fausch, Steven   Asundi, Jyoti   Kolumam, Ganesh   Zhang, Chunlian   Zavala-Solorio, Jose   Donnelly-Roberts, Diana   Challagundla, Malleswari   Boch, Christina   Cao, Charlie   Mohler, Eric   Sidrauski, Carmela   Bonkowsky, Joshua   Jeong, Anna   Cho, William   

Session Name:P2: Child Neurology and Developmental Neurology: Pediatric White Matter  

Topic:Child Neurology and Developmental Neurology  

Program Number:P2.001  

Author Institution:Calico Life Sciences, South San Francisco, CA  AbbVie, North Chicago, IL  AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany  Abbvie, North Chicago, CA  University of Utah, Salt Lake City, UT  

Seizures in the Leukodystrophies

Author:Hackett, Ashley   Liu, Katie   Yan, Helena   Corre, Camille   Gao, Kerry   Kelly, Daniel   Ghabash, Gabrielle   Goodman, Jordan   Benko, William   Thompson-Stone, Robert   Fatemi, Ali   Raymond, Gerald   Keller, Stephanie   Eichler, Florian   Escolar, Maria   Bonkowsky, Joshua   Mallack, Eric   

Session Name:P6: Epilepsy/Clinical Neurophysiology (EEG): Epilepsy Syndromes and Genetics 1  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P6.001  

Author Institution:Emory University/Children’s Healthcare of Atlanta, Atlanta, GA  Emory University, Atlanta, GA  Weill Cornell, New York, NY  University of Rochester, Rochester, NY  Harvard University, Atlanta, GA  University of Utah, Salt Lake City, UT  Kennedy Krieger Institute, Baltimore, MD  University of California Davis, Davis, CA  Johns Hopkins, Baltimore, MD  Massachusetts General Hospital, Boston, MA  Children’s Hospital of Pittsburgh, Pittsburgh, PA  

A Novel Mouse Model of Cerebral Demyelination in X-linked Adrenoleukodystrophy Highlights NLRP3 Activation in Lesion Pathogenesis

Author:Hashemi, Ezzat   Srivastava, Isha   Aguirre, Alejandro   Yoseph, Ezra   Kaushal, Esha   Awani, Avni   Ryu, Jae   Talebian, Shahrzad   Chu, Pauline   Steinman, Lawrence   Orchard, Paul   Lund, Troy   Han, May   Bonkowsky, Joshua   Van Haren, Keith   

Session Name:P11: General Neurology: Novel Concepts  

Topic:General Neurology  

Program Number:P11.004  

Author Institution:Stanford University School of Medicine, PALO ALTO, CA  Gladstone Institute for Neurological Disease, San Francisco, CA  Stanford University School of Medicine, Stanford , CA  University of Minnesota, Minneapolis, MN  Stanford University School of Medicine, Stanford, CA  University of Utah School of Medicine, Salt Lake City, UT