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Next Generation Prodrug Troriluzole: Increased Bioavailability of Riluzole with No Food Effect in Healthy Subjects

Author:Sevinsky, Heather   Rozakis, Rachel   Nepomuceno, Tracy   Malatesta, Jo Ann   Awsare, Bharat   Ashbrenner, Eric   Kaplita, Stephen   Gentile, Kimberly   Hussey, Elizabeth   Qureshi, Irfan   Coric, Vladimir   Bertz, Richard   

Session Name:S5: ALS and CMT: New Therapeutic Approaches  

Topic:Neuromuscular and Clinical Neurophysiology (EMG)  

Program Number:S5.006  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven , CT  Allucent, Cary, NC  Biohaven Pharmaceuticals, Inc, New Haven, CT  Certara, Inc, Princeton, NJ  Biohaven Pharmaceuticals, Inc, New Haven, CT  Biohaven Pharmaceuticals, Inc, Cheshire, CT  

Safety, Tolerability, and Pharmacokinetics of Single and Multiple Rising Doses of a Next Generation Prodrug Troriluzole in Healthy Subjects

Author:Sevinsky, Heather   Awsare, Bharat   Rozakis, Rachel   Gentile, Kimberly   Mydlow, Patricia   Ashbrenner, Eric   Ham, Rachel   Stock, David   Qureshi, Irfan   Coric, Vladimir   Bertz, Richard   

Session Name:P4: General Neurology: Neuroimmunology  

Topic:General Neurology  

Program Number:P4.012  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  Allucent, Cary, NC  

No Clinically Relevant Effects of Hepatic Impairment on the Pharmacokinetics of a Next Generation Prodrug Troriluzole

Author:Bertz, Richard   Rozakis, Rachel   Donohue, Mary   Sevinsky, Heather   Awsare, Bharat   Kaplita, Stephen   Hussey, Elizabeth   Qureshi, Irfan   Coric, Vladimir   

Session Name:P4: General Neurology: Neuroimmunology  

Topic:General Neurology  

Program Number:P4.014  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  Allucent, Cary, NC  

Phase 1 Study Evaluating the Safety and Tolerability of BHV-7000, a Novel, Selective Kv7.2/7.3 Potassium Channel Activator, in Healthy Adults

Author:Awsare, Bharat   Lerner, Jason   Ashbrenner, Eric   Sevinsky, Heather   Bozik, Michael   Dworetzky, Steven   Donahue, Lia   Killingsworth, Randall   Francoeur, Bruno   Qureshi, Irfan   

Session Name:P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials and Outcomes  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P8.007  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  Syneos Health, Quebec, QC, Canada  

Novel, Selective Kv7.2/7.3 Potassium Channel Activator, BHV-7000, Demonstrates Dose-dependent Pharmacodynamic Effects on EEG Parameters in Healthy Adults

Author:Lerner, Jason   Awsare, Bharat   Sevinsky, Heather   Ashbrenner, Eric   Killingsworth, Randall   Kendrick, Racheal   Vereycken, Emiel   Colenbrier, Nigel   Neuray, Caroline   van Mierlo, Pieter   Slater, Jeremy   Wyatt, David   Qureshi, Irfan   Dworetzky, Steven   Bozik, Michael   

Session Name:P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials and Outcomes  

Topic:Epilepsy/Clinical Neurophysiology (EEG)  

Program Number:P8.011  

Author Institution:Biohaven Pharmaceuticals, Inc, New Haven, CT  Certara, Inc, Princeton, NJ  Epilog, Clouds of Care NV, Ghent, Belgium  Stratus, Irving, TX  Syneos Health, Quebec, QC, Canada