We describe a novel system for electrophysiologic mapping and brain-computer interface technology, comprising conformable thin-film electrode arrays and a minimally invasive surgical delivery system that together facilitate bidirectional data exchange from large portions of the cortical surface. 

We demonstrate the feasibility and safety of delivering reversible, 1024-electrode implants to multiple functional regions of the human brain intraoperatively in a first-in-human study of five neurosurgical patients in anesthetized and awake states

The system allows high-density neural recording at spatial and temporal resolutions not previously possible, real-time visualization of cortical surface activity, and accurate neural decoding of motor and speech intent. Additionally, the system facilitates functional localization: it is able, in seconds, to map and display the phase-reveral boundary between primary somatosensory and primary motor cortex with 400-micron resolution, in a manner that can support real-time intraoperative decision-making. 

These results demonstrate the highly scalable nature of micro-electrocorticography.

This demonstrates utility for next-generation neural interfaces with a favorable safety profile for human use.